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Virology

Coliphage PR772 evaluated for use in virus filter performance testing

Published in Proteomics Weekly, October 18th, 2004

Researchers have characterized coliphage PR772 and evaluated its potential for virus filter performance testing.

"Virus filtration is a key clearance unit operation in the manufacture of recombinant protein, monoclonal antibody, and plasma-derived biopharmaceuticals. Recently, a consensus has developed among filter manufacturers and end users about the desirability of a common nomenclature and a standardized test for classifying and identifying virus-retentive filters. The Parenteral Drug Association virus filter task force has chosen PR772 as the model bacteriophage to standardize nomenclature for large-pore-size virus-retentive filters (filters designed to retain...

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