Published in Proteomics Weekly, November 15th, 2004
"We have initiated comparative genomic analysis of Mycobacterium avium subspecies by DNA microarray, uncovering 14 large sequence polymorphisms (LSPs) comprising over 700 kb that distinguish M. avium subspecies avium from M. avium subspecies paratuberculosis," an international team of investigators reports.
"Genes predicted to encode metabolic pathways were over-represented in the LSPs, and analysis revealed a polymorphism within the mycobactin biosynthesis operon that potentially explains the in vitro mycobactin dependence of...
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