Drug Development
Scaffold-stabilized peptides foster the identification of new drug targets
Published in Proteomics Weekly, December 13th, 2004
"Small peptides that perturb intracellular signaling pathways are useful tools in the identification and validation of new drug targets. To facilitate the analysis of biologically active peptides, we have developed retroviral vectors expressing an intracellular scaffold protein that significantly enhances the stability of small peptides in mammalian cells," scientists writing in the British Journal of Cancer state.
"This approach was chosen because retroviral transduction results in efficient and controlled delivery of the gene encoding the effector peptide, while the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Proteomics Weekly
Source: Proteomics Weekly (2004-12-13)
More Articles from Proteomics Weekly
- Cancer Therapy
G-quartet oligonucleotides targeting Stat3 protein fight cancer growth - Development
p38 pathway regulates transcription, translation of Akt during myogenesis - Hormones
Estrogen controls branched-chain amino acid catabolism in female rats - Phosphorylation
Norepinephrine regulation and diurnal rhythm of protein kinase phosphorylation - Renal Disease
Fatty acid-binding protein in urine denotes proximal tubule stress overload - AIDS/HIV Vaccine
Recall antigen activation induces prompt release of CCR5 ligands from PBMC - More from this issue of Proteomics Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
