HIV/AIDS Vaccine

Neutralization profiles of HIV-1 by monoclonal antibodies presented

Published in Proteomics Weekly, February 14th, 2005

Researchers present neutralization profiles of newly transmitted human immunodeficiency virus type 1 by monoclonal antibodies 2G12, 2F5, and 4E10 in a recent issue of the Journal of Virology.

"As the AIDS epidemic continues unabated, the development of a human immunodeficiency virus (HIV) vaccine is critical. Ideally, an effective vaccine should elicit cell-mediated and neutralizing humoral immune responses. We have determined the in vitro susceptibility profile of sexually transmitted viruses from 91 patients with acute and early HIV-1 infection to three monoclonal antibodies, 2G12, 2F5, and 4E10," researchers in the United States and Austria report.

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Source: Proteomics Weekly (2005-02-14)

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