Pharmacology

Rebamipide analyzed, pharmacological behavior clarified

Published in Proteomics Weekly, February 14th, 2005

Recently published research from South Korea has reported on the pharmacological characterization of rebamipide.

"We previously reported that rebamipide (2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]-propionic acid) generated oscillations of intracellular Ca²⁺ concentration ([Ca²⁺](i)) probably through the activation of cholecystokinin type 1 (CCK1) receptors in rat pancreatic acinar cells. Therefore, in the present study, we aimed to establish the pharmacological characteristics of rebamipide in rat pancreatic acinar cells," reported S.J. Moon and colleagues.

"CCK-8S and rebamipide inhibited ^I125BH-CCK-8S...

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Source: Proteomics Weekly (2005-02-14)

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