Proteomics

Drosophila training of pheromonal cues enhanced by a protein kinase

Published in Proteomics Weekly, February 14th, 2005

Researchers from the United States have reported that a Drosophila central nervous system (CNS) protein kinase enhances the training of pheromonal cues.

"Calcium/calmodulin-dependent protein kinase II (CaMKII) is abundant in the CNS and is crucial for cellular and behavioral plasticity. It is thought that the ability of CaMKII to autophosphorylate and become Ca²⁺ independent allows it to act as a molecular memory switch.

"We have shown previously that inhibition of Drosophila CaMKII leads to impaired performance in the courtship conditioning associative memory assay, but it was unknown whether the constitutive form of the kinase had a...

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Source: Proteomics Weekly (2005-02-14)

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