DNA Vaccine

DNA-encoding chicken IL-6 and E. coli protein stimulate antibodies

Published in Proteomics Weekly, February 14th, 2005

A plasmid-DNA-encoding chicken interleukin-6 and Escherichia coli K88 fimbrial protein FaeG stimulate the production of anti-K88 fimbrial antibodies in chickens.

According to recent research from Canada, "Immunization using a plasmid to deliver an encoded protein for expression in situ as the antigen is a promising technology. A plasmid encoding the enterotoxigenic Escherichia coli K88 fimbrial protein FaeG when injected into chickens stimulates the production of antibodies against the fimbrial protein, similar to what has been observed in mice. The efficacy of a genetic adjuvant on fimbrial antibody production was tested by introducing the gene for...

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Source: Proteomics Weekly (2005-02-14)

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