Proteomics Weekly
Susan Hasty, Publisher
Table of Contents . . . March 21st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Proteomics Weekly | Other Publications
Alzheimer Disease - CLAC protein studied, amyloid beta-peptide-binding site identified
Apoptosis - Apoptosis of osteoblast-like cells studied, role of surface attachment revealed
Bleomycin - Bleomycin-induced lung fibrosis studied, carbon monoxide suppression revealed
Disease Associations - Prion disease incubation time studied, effect of dynein mutation clarified
Platelets - Sildenafil studied, effect on human platelet secretory function clarified
ACE Inhibitors - Cardioprotection of zofenopril is greater than non-sulphydryl ACE inhibitors
Actins - ADP-F-actin analyzed, intermediate form detected
Actomyosin - Role of actomyosin motor in Elodea canadensis cytoplasmic streaming studied
Addison Disease - Diabetes plus 21-hydroxylase antibodies raises Addison disease risk
Adenosine Receptors - Adenosine receptor antagonists studied, target- and ligand-based drugs modeled
Adrenoceptors - Adrenoceptor fusion protein studied, role in G protein palmitoylation revealed
Atherosclerosis - Studies describe new findings in atherosclerosis research
Airway inflammation - Study examined role of JNK in structural changes of the airway
Alzheimer Disease - A-beta vaccination affects plaque pathology in absence of encephalitis
Alzheimer Disease - Pin1 plays key role in preventing age-related neurodegeneration
Alzheimer Disease - Presenilin2 and variant overexpression studied, effect of calcium entry shown
Alzheimer Disease - Rapid assembly of amyloid-beta peptide studied, consequences clarified
Alzheimer Disease - Research in Alzheimer disease provides new insights
Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge
Alzheimer Disease - Traffic jam on axon highway occurs early in Alzheimer
Amyloid Fibrils - Amyloid fibril formation analyzed, involvement of adenovirus fiber revealed
Amyloid Fibrils - Amyloid-like fibril formation studied, beta-microglobulin peptide implicated
Amyloid Fibrils - Molecular basis for amyloid fibril formation and stability
Angiology - Calcium-independent phospholipase studied, regulation clarified
Angiology - Inhibiting MMPs could ameliorate intimal thickening, prevent MI
Diabetes Pathogenesis - Research add new data to diabetes pathogenesis body of knowledge
Angiology - Recent findings illuminate research in angiology
Angiotensin - Adrenal glomerulosa cell physiology studied, effect of angiotensin shown
Angiotensinase - Angiotensinase activity studied, asymmetrical brain distribution revealed
Anion Channels - Astrocyte osmolyte release studied, role of calcium-sensitive mechanisms shown
Antidepressants - Venlafaxine modulates restraint-induced hippocampal proteins in rats
Antimicrobials - Myrothecium cinctum antifungal antibiotic analyzed, properties clarified
Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights
Apoptosis - Mitochondria-dependent apoptosis studied, blockage by cypermethrin documented
Apoptosis - Nature of Anaplasma phagocytophilum neutrophil apoptosis inhibition revealed
Apoptosis - Testicular germ cell induced apoptosis analyzed, role of p53 protein clarified
Arrestins - Chemoattractant receptor trafficking analyzed, inhibition by arrestins revealed
Assisted Reproduction - Anti-hyaluronidase oligosaccharide analyzed, influence on polyspermy revealed
Assisted Reproduction - Infected sperm transmits hepatitis B to early embryonic cells
Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis
Astrocytes - Manganese-induced astrocyte stellation studied, role of RhoA inactivation shown
Atherosclerosis - Harvard inks agreement to launch major genotyping study in atherosclerosis
Atherosclerosis - New findings in atherosclerosis described
Autoimmune Disease - Autoantibody forms in patients with chronic viral hepatitis
B-Cell Lymphoma - TCL1A overexpression linked to poor outcome in DLCL patients
Diabetes Pathogenesis - Researchers publish new studies and findings in the area of diabetes pathogenesis
Barrett Carcinogenesis - Cell-cycle phase abnormalities don't account for disordered proliferation
Biochemistry - Novel microfluidic chip devised for cellular metabolic analysis
Biomedical Engineering - Coded nanoparticles present a way to monitor transfection after gene delivery
Biomedical Engineering - Effect of lypholization on some therapeutic recombinant proteins studied
Biomedical Engineering - Life sciences company launches functional p53 protein microarray
Biomedical Engineering - Scientific instruments maker signs manufacturing agreement with JEOL Ltd.
Immunology - Studies add new findings to immunology body of knowledge
Biotechnology - Microchip-based affinity capillary electrophoresis system developed
Body Composition - Deiodinase polymorphism linked to body composition in humans
Bone Development - TGF-beta regulates collagen type V alpha1 in osteoblasts
Bovine Herpesvirus - Bovine herpesvirus gene promotes virus growth and reactivation
Breast Cancer - Cytotoxic mechanisms of 15dPG-J2 determined
Breast Cancer - Masking of erbB2 may underlie Herceptin resistance
Malaria Vaccines - Studies advance knowledge in malaria vaccines research
Breast Cancer - Peptide assay variability in IGF-I-based risk estimates compared
Business & Finance - Pharma company announces financial results
Business Update - Carna named exclusive distributor for kinase crystallization products, services
Business Update - Collaboration formed to develop next-generation human growth hormone
Business Update - Company announces implant of cryopreserved osteoarticular allograft
Business Update - Company updates PAR-2 program in oncology and inflammation
Neuroscience - Researchers publish new studies and findings in the area of neuroscience
Business Update - Fun City Popcorn changes to new company name and trading symbol
Business Update - Sentigen Holding Corp. Announces the Sale of Its Specialty Media Division
Cancer Therapy - Antagonists to melanoma-inhibiting activity foil immunosuppression
Cancer Therapy - Findings advance knowledge in cancer therapy research
Cancer Therapy - Infusions of gene therapy-sponge mixtures may beat human liver cancer
Cancer Vaccines - Amino acid substitution improves enzymatic stability of MUC2 epitope
Obesity Pathogenesis - Researchers describe findings in obesity pathogenesis studies
Cancer Vaccines - B-lymphocytes activated by CD40 ligand induce anti-tumor response
Cancer Vaccines - Distinct overlapping T helper epitopes found in 37-58 region of SSX-2
Cancer Vaccines - Findings describe new data in cancer vaccines research
Cancer Vaccines - PLGA microspheres improve antigen delivery to dendritic cells
Cancer Virology - New binding target for oncogenic viral protein revealed
Proteomics - Recent findings in proteomics provide new insights
Cardiac Hypertrophy - Study examined mechanisms of hypertrophic growth in absence of NPRA signaling
Cardiac Hypertrophy - Yin Yang 1 decreases alpha-MyHC mRNA, protein expression in ventricular myocytes
Cardiology - Researchers detail new studies and findings in the area of cardiology
Cardiology - Tryptase is proangiogenic in the healing heart
Cardiovascular Disease - Mechanism may contribute to clinical link between myeloperoxidase and CV disease
Cardiovascular Research - L-type Ca2+ channels are regulated by beta-adrenergic stimulation
Virology - Studies add new findings to virology body of knowledge
Cell Biology - Mitotic checkpoint protein BubR1 regulates chromosome-spindle attachment
Cell Biology - Virologists illuminate HIV cell activity
Cell Proliferation - Cell migration inhbited, nature of MEK1-mediated restoration clarified
Cell Transport - Digoxin transport and interaction studied, pharmacokinetics clarified
Chemokine Receptors - Recovery after ozone exposure studied, role of CXCR2 revealed
Chromosome Structure - Mammalian protein SCP1 studied, synaptonemal complex-like structures revealed
Cognitive Diseases - Alzheimer and FTDP-17 models studied, increased tau phosphorylation revealed
Collagen - Arabidopsis prolyl 4-hydroxylase studied, substrate specificity clarified
Colon Cancer - Osteopontin promotes tumor progression in multiple ways
Colorectal Cancer - Research company awarded grant to study DNA mutations in colorectal cancer
Congestive Heart Failure - ACE inhibitors demonstrate a class effect for treatment of patients with CHF
Contraception - Chicken riboflavin carrier protein has immunocontraceptive potential
Coronary Heart Disease - A three allelic SNP is strongly associated with plasma CRP concentration
Cyclins - Candida albicans hyphal development studied, role of cyclin Cln3p revealed
Cytomegalovirus Vaccine - Cytomegalovirus glycoprotein H induces mucosal and systemic immunity
DNA Vaccine - Bacterial DNA-specific modified base triggers cytokine production in mice
Deerpox Virus - Genome of deerpox virus reported
Dental Caries - Microparticles promote immunogenicity of Streptococcus peptide
Depression - Company initiates phase I trial with triple-reuptake inhibitor for depression
Diabetes Complications - Genetic differences control susceptibility to diabetic retinopathy
Diabetes Genomics and Genetics - Genetic factors in type 2 diabetes reviewed
Diabetes Genomics and Genetics - Recent findings in diabetes genomics and genetics provide new insights
Diabetes Pathogenesis - GLUT1 transporter protein expression reduced in type 2 diabetes
Diabetes Pathogenesis - Glutathione utilization rate increased in poorly controlled diabetes
Diabetes Pathogenesis - Increased hepatocyte protein expression promotes diabetes phenotype
Diabetes Pathogenesis - Mitochondrial dysfunction and type 2 diabetes reviewed
Diabetes Pathogenesis - Protein kinase activity contributes to hyperphagia in diabetes
Diabetes Pathogenesis - Recent studies add new data to diabetes pathogenesis research
Diabetes Therapy - Findings describe new data in diabetes therapy research
Diabetes Therapy - Free fatty acids regulate gut incretin glucagon-like peptide-1
Diabetic Neuropathy - Reports add new data to diabetic neuropathy research
Diet and Nutrition - Diets decrease C-reactive protein by affecting adipocyte function
Diet and Nutrition - Lipids modify age-associated changes in intestinal uptake of fructose
Disease Associations - Streptococcus pneumoniae FtsA protein studied, properties revealed
Disease Associations - Trypanosoma brucei glycoproteins analyzed, carbohydrate chains revealed
Disease Associations - Alpha-ketoglutarate dehydrogenase complex studied, inhibition revealed
Disease Associations - CFTR folding analyzed, contributions of side chain and backbone revealed
Disease Associations - Cerulein-induced acute pancreatitis studied, protective effect revealed
Disease Associations - Dry eye studied, beneficial role of matrix metalloproteinase knockout shown
Disease Associations - Effects of cigarette smoke studied, physiological inhibitions revealed
Disease Associations - Leukocyte heat-shock induction studied, role of electromagnetic fields clarified
Drug Abuse - Dopamine study sheds new light on drug addiction
Drug Delivery - Copolymer films transport therapeutic protein to vascular endothelial cells
Drug Design - Scientists discover the origin of a mysterious physical force
Drug Development - Novel MAb fragment alters M2 muscarinic acetylcholine receptor activity
Drug Development - P3 and P4 moieties analyzed, novel binding of factor VIIa inhibitor revealed
Drug Development - Somatostatin agonists may control tumor neovascularization
Drug Development - ToxShield Suite launched
Ectodomain Shedding - Ectodomain shedding analyzed, influence of oxidative stress revealed
Endocrinology - Agouti-related peptide studied, suppression of hormone release revealed
Endocrinology - Endoplasmic reticulum stress contributes to insulin resistance and diabetes
Endocrinology - Excess resistin production alters lipid levels in mice
Endocrinology - Prohormone convertase studied, role in glucagon formation revealed
Endocrinology - Sodium channels studied, effects of deglycosylation clarified
Endocytosis - Keratinocyte growth factor receptor studied, role of tyrosine residue revealed
Endometrial Cancer - MIS inhibits proliferation of cell lines expressing MIS type II receptor
Endometrial Carcinoma - Tissue microarray used to identify cancer-testis antigens
Endometriosis - Enhanced gene expression may confer resistance to cytokine-induced apoptosis
Endothelial Cells - Microtubules involved in thrombin-induced endothelial barrier dysfunction
Enzymology - Escherichia coli dCTP deaminase studied, behavior determined
Enzymology - Escherichia coli oxidoreductase studied, iron-sulfur cluster characterized
Enzymology - Cyclooxygenase-2 inhibition has a selective effect on endothelial cell growth
Enzymology - Peptidylarginine deiminases studied, enzymatic properties compared
Essential Tremor Disease - Findings may help explain cause of most common movement disorder
Finance - Company focused on protein deficiency treatments reports strong 2004 financials
Finance - DX-88 and DX-890 maker reports increased net loss
Finance - Genomics company reports increased revenue, decreased losses for 2004
Finance - Sale of BioSepra chromatography business affects financial results
Gastroenterology - Researchers provide details of new studies and findings in the area of gastroenterology
Gene Expression - Interleukin regulation of gene expression studied, role of adherence shown
Gene Research - Controlled conditions allow laboratories to conduct collaborative gene studies
Gene Research - Knockout mice show interleukin-6 helps the brain cope with injury
Gene Research - Nonenzymatic nucleic acid labeling kits for DNA microarray applications launched
Gene Research - Single-base extension reactions recognize multiple polymorphisms simultaneously
Gene Transfer - mRNA nucleofection transfects murine macrophages
Genetic Disorders - Escherichia coli dihydrofolate reductase studied, effects of oxidation shown
Gonorrhea - Genetic typing of porin protein of Neisseria gonorrhoeae reported
Growth Cones - Growth cones studied, movement in a peptide gradient documented
Growth Factor Receptors - Fibroblast receptor studied, role of a novel intronic cis element clarified
Gynecology - Molecular markers indicate the presence of cervical cancer
HIV/AIDS Encephalitis - Increased FKBP12 may explain vulnerability of basal ganglia to HIV infection
HIV/AIDS Mental Health - Substance P has role in pathophysiology of stress/depression in HIV infection
HIV/AIDS Pathogenesis - Amyloid precursor protein may facilitate monocyte entry into brain
HIV/AIDS Pathogenesis - Conformational flexibility retained in HIV-1 Rev-RNA complexes
HIV/AIDS Pathogenesis - LEDGF/p75 prevents proteasomal degradation of HIV-1 integrase
HIV/AIDS Pathogenesis - MCP-1-2578G allele associated with elevated MCP-1 in cerebrospinal fluid
HIV/AIDS Pathogenesis - Macrophage-secreted MMP 9 is down-regulated following HIV-1 infection
HIV/AIDS Pathogenesis - Urokinase plasminogen activator receptor important in HIV-associated dementia
HIV/AIDS Research - Tissue culture model analyzes macrophage activation in the brain
HIV/AIDS Therapy - Antiretroviral enfuvirtide is not an inhibitor of p450 cytochrome
HIV/AIDS Therapy - Molecular basis determined for GLUT4 inhibition by protease inhibitors
HIV/AIDS Therapy - Protein found in cells may be the key to controlling HIV
HIV/AIDS Vaccine - Anti-HIV antibodies require few residues to neutralize HIV-1
HIV/AIDS Vaccine - Antibodies to HIV vif turns HIV infection into benign problem
HIV/AIDS Vaccine - Antibody response elicited by trimeric HIV glycoproteins analyzed
HIV/AIDS Vaccine - Clinical evaluation of HIV/AIDS vaccine initiatied
HIV/AIDS Vaccine - Differential immune containment of HIV-1 clade B strains found
HIV/AIDS Vaccine - Expression of gag protein of HIV-1CN in Pichia pastoris reported
HIV/AIDS Vaccine - Inducing murin CCR5-downregulating antibodies prevents HIV infection
HIV/AIDS Vaccine - Macaque MHC molecules presenting immunodominant SIV epitopes analyzed
HIV/AIDS Vaccine - Modified HIV envelope proteins exhibit enhanced binding to antibodies
Heart Failure - Lack of trials limits application of differences in B-adrenoreceptor antagonists
Helicobacter Vaccines - New findings in helicobacter vaccines described
Hematology - Myelofibrosis with myeloid metaplasia formation and VEGF levels often parallel
Hematology - New findings in the area of hematology described
Hemolytic-Uremic Syndrome - Inhibition of p38 MAPK may prevent HUS-related brain damage
Heparin - Fibroblast growth factor mutations analyzed, evidence for model presented
Hepatology - Rho-kinase and MLCK regulate sinusoidal endothelial fenestrae organization
Herpesvirus Vaccine - Cutaneous antigen expression by herpes-specific lymphocytes explored
Herpesvirus Vaccine - Ocular delivery of herpes epitopes induces local and systemic responses
Histamine Receptors - Norepinephrine exocytosis analyzed, nature of attenuation clarified
Histones - Histone code analyzed, role in corepressor complex repression clarified
Hodgkin Lymphoma - Chk2 expression may be downregulated in HL cells via epigenetic mechanisms
Hormone Replacement Therapy - HRT may improve oxidative stress and lipoprotein metabolism in older women
Human Papillomavirus Vaccine - Human papillomavirus oncoprotein vaccine eradicates established tumors
Hypertension - Small increase in systolic BP may increase the burdens of CV disease
Hypertension Therapy - Efficacy of triple vasopeptide inhibition determined
Immunology - Autologous IgG with the inflammation-associated marker is immunogenic
Immunology - Computational model of selectin-mediated leukocyte rolling developed
Immunology - Research add new data to immunology body of knowledge
Infectious Laryngotracheitis Virus - Relevance of infectious laryngotracheitis virus gJ proteins reviewed
Information Technology - Automated culture-independent molecular analysis system launched
Information Technology - National institute picks supercomputer for protein structure analysis
Insecticides - Bacillus thuringiensis cytolytic toxin studied, mechanism of action revealed
Integrase - Holliday junction resolution studied, role of integrase protomers revealed
Interleukins - Normal platelets possess the soluble form of IL-6 receptor
Intestinal Smooth Muscle - Smooth muscle Y receptors and signaling pathways studied, expression clarified
Ion Channels - Potassium channel RCK domain studied, electrostatic interaction clarified
Ischemia - Hippocampal forebrain ischemia analyzed, XIAP and Smac/DIABLO regulation defined
Kallikreins - Stratum corneum examined, proteolytic cascade of kallikreins revealed
Kinase - Dictyostelium PakB studied, properties of constitutively activated form revealed
Kinase Pathways - Kinase pathways studied, role of receptor occupancy in activation revealed
Leptin Studies - Assay of renal Na+-ATPase and regulation in obesity conducted
Leptin Studies - Metabolic regulation of leptin production in adipocytes investigated
Leptin Studies - Recent findings in leptin studies provide new insights
Ligand Binding - CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
Lipid Research - Lipid profiles improve in gene-deficient mice after cell therapy
Lipoproteins - Escherichia coli lipoprotein studied, nature of mislocation clarified
Lung Cancer - Researchers learn why some lung cancers stop responding to erlotinib, gefitinib
Malaria Vaccine - Baculovirus-based malaria vaccine shows promise in Senegalese village
Malaria Vaccine - Epitope mapping of malaria parasite inhibitory antibodies reported
Malaria Vaccine - Modified HRP-I peptide analogue protects against malaria
Malaria Vaccines - Reports add new data to malaria vaccines research
Malignant Mesothelioma - Mesothelial marker D2-40 may be useful in differential diagnosis
Melanoma Vaccine - Peptide vaccine has minimal benefit in patients with stage IV melanoma
Melanoma Vaccine - Vaccine induces T cell response against tumor antigen survivin
Melanoma Vaccines - Findings advance knowledge in melanoma vaccines research
Memory - Molecule important in cell construction also critical in learning and memory
Meningitis Vaccine - Neisseria meningitidis proteins reduce bacteremia in infant rats
Meningitis Vaccine - Neisseria NadA promotes bacterial penetration into epithelial cells
Metamorphosis - Red blood cells studied, low-temperature transcriptional arrest clarified
Microvascular - Therapies designed to block endothelial CEACAM1 may fight cancer
Morbid Obesity - Adiposity plays role in obesity-related, low-grade inflammation
Mucosal Immunization - Reports describe recent advances in mucosal immunization research
Muscular Dystrophy - Corrective oligodeoxynucleotides show strand bias during dystrophin gene repair
Mutagenesis - Enterococcus faecalis lsa locus studied, differences clarified
Myeloma - "Smart" immune cells kill more cancer
Natural Products - San-Huang-Xie-Xin-Tang studied, effect on hypotension and inflammation shown
Neurodegeneration - New findings in neurodegeneration described
Neurodegenerative Disorders - Hippocampal spine synapse formation studied, role of estradiol isomers revealed
Neurology - Neuronal differentiation studied, molecular mechanisms clarified
Neuroscience - CGRP receptors may regulate gene transcription in primary afferent neurons
Neuroscience - Drug targeting studied, impact of P-glycoprotein evaluated
Neuroscience - Effect of hypothalamic neuropeptide Y on ethanol consumption determined
Neuroscience - Eosinophil-induced signaling in cholinergic nerve cells characterized
Neuroscience - MAP1b has microtubule-stabilizing activity in growing axons
Neuroscience - Microdialysis/CE system enables monitoring of five neurotransmitters in rats
Neuroscience - Novel system enables simultaneous monitoring of 5-HT, NA and DA in rat brain
Neuroscience - Researchers detail new studies and findings in the area of neuroscience
Neuroscience - The 14-3-3 protein mediates tau phosphorylation by SGK1
Neurotrophin - Neurotrophin-dependent behavior studied, role of HIKE domain of TrkA indicated
Neutrophil Migration - Neutrophil migration analyzed, role of activated signal kinase revealed
Nocturia - Japanese pharmaceutical company in-licenses urology drug from Otsuka
Notch Signaling - Notch signaling system analyzed, distinct roles of EGF repeats revealed
Obesity Pathogenesis - Changes of hypothalamic peptide expression in obese rats reported
Obesity Pathogenesis - Hepatic gene expression profiles altered by genistein in obesity
Obesity Pathogenesis - Recent studies add new data to obesity pathogenesis research
Obesity Therapy - Findings advance knowledge in obesity therapy research
Obesity and Diabetes - Diet-induced obesity upregulates glucocorticoid metabolism
Obesity and Diabetes - Protein secreted by visceral fat mimics effects of insulin
Obstetric Anesthesia - Measuring beta-trace protein may aid diagnosis of CSF-cutaneous fistula
Obstetrics - Identifying protein biomarkers predicts success for cervical stitching
Oncology - Anastellin arrests the growth of human microvessel endothelial cells
Oncology - Antiangiogenic gene therapy may be a valuable adjuvant for chemotherapy
Oncology - Antiangiogenic genes prevent secondary metastasis after primary tumor removal
Oncology - Gene silencing sensitizes prostate cancer to cancer therapy
Oncology - Protein antagonists reduce the metastatic potential of melanoma
Oncology - Researchers describe findings in oncology studies
Ophthalmology - Effects of Ang II on pericyte-containing retinal microvasculature clarified
Orthopedics - Statins hasten new bone formation in healing bones
Ovarian Cancer - ApoE required for cell proliferation, survival in apoE-expressing cancer cells
Ovarian Cancer - Class III beta-tubulin overexpression a key mechanism of paclitaxel resistance
Patents - Company files for patents on cancer genes
Patents - Life sciences company files patent applications for mad cow disease blood test
Peptide Elongation Factors - Proteasome-mediated protein degradation studied, elongation factor revealed
Peptide Receptors - Ligand binding studied, role of calcitonin receptor-like receptor revealed
Peptide Synthesis - Synthesis of external beta-turn templates studied, reaction documented
Periodontal Disease - Porphyromonas gingivalis protein antisera causes phagocytosis
Physiology - Blood-brain barrier transport studied, effect of lipopolysaccharide shown
Physiology - SERCA2a calcium pump mRNA stability studied, role of specific domains revealed
Physiology - Starvation in yeast investigated, role of autophagy clarified
Pituitary Glands - Heparin and activin-binding determinants in follistatin and FSTL3 determined
Pneumococcal Vaccine - Streptococcus iron-uptake lipoproteins elicit antibody responses
Pneumonia - Mycoplasma pneumoniae antigen with diagnostic value isolated
Presenilin - Endoproteolysis of presenilin studied, role of PEN-2 domain revealed
Prions - Cytosolic degradation of prion studied, role of calpain revealed
Prions - Researchers' data advance prions research
Product Licensing - Pharma company licenses novel anticancer compounds
Prostate Cancer - 3alpha-diol stimulates prostate cell proliferation via EGF-like pathway
Prostate Cancer Therapy - Phosphoglycerate mutase B is molecular target of resveratrol
Prostate Cancer Vaccines - Researchers' findings advance prostate cancer vaccines research
Protease - Escherichia coli suicide studied, role of activating peptide revealed
Protein Denaturation - Denaturant sensitivities of proteins analyzed, contributions dissected
Protein Folding - DnaK-dependent folding studied, mutagenic alteration of process described
Protein Kinase - DNA damage analyzed, selective and different kinase specificities revealed
Protein Precursors - Myelin expression abnormalities analyzed, role of Fyn clarified
Protein Signals - Caenorhabditis elegans DAZ-1 studied, roles during oogenesis clarified
Protein Signals - Article reviews components of NADPH oxidases in leukocytes and vascular tissue
Protein Signals - CD38 cleavage in induced chemotaxis studied, roles of kinases clarified
Protein Translocation - Pseudomonas syringae secretion chaperones studied, protective role revealed
Proteomics - Angiogenin is essential for endothelial cell proliferation and angiogenesis
Proteomics - Findings in proteomics provide new insights
Proteomics - Novel in-line sample purification method developed for MALDI-MS
Proteomics - Peptide:N-glycanase glycoprotein turnover probed
Proteomics - Protein preconcentration technique improves microfluidic analysis
Proteomics - Tenomodulin is involved in tenocyte proliferation but not angiogenesis
Pseudomonas Aeruginosa - P. aeruginosa LigD analyzed, polymerase function clarified
Pulmonary Medicine - VEGF-A changes lung morphogenesis in the developing mouse
RNA Binding Proteins - Bacillus subtilis TRAP analyzed, direction of RNA binding revealed
Receptor Studies - Receptor activation minimizes signaling which leads to hypertrophic responses
Receptor Studies - Studies have identified protease-activated receptors in vasculature and heart
Renal Cell Carcinoma - Expression of Kank in RCC characterized
Renal Disease - Kidney surface gene transfer features selective transgene expression
Renal Medulla - Renal medullary gene expression characterized in aquaporin-1 null mice
Reperfusion - Oxidative cell death studied, role of dimished neuron phosphorylation clarified
Respiratory Syncytial Virus - Intranasal siRNA nanoparticles inhibit respiratory syncytial virus
Resveratrol - Resveratrol's cancer prevention may result from changes in cell cycle progress
Retinitis Pigmentosa - Retinitis pigmentosa analyzed, association of causative genes revealed
Retinopathy - Complement activation produces laser-induced choroidal neovascularization
SARS Vaccine - Binding system restores interaction between SARS protein and receptor
Salmonella Vaccine - Absence of substance P receptor enhances IgA response
Salmonella Vaccine - Regulation of cytokine Salmonella-induced mRNA expression examined
Salmonella Vaccine - Type 1 fimbriae protects laying hens against Salmonella
Sepsis - Immunogenicity of brominated protein reported
Shigellosis Vaccine - Shigella flexneri vaccine strains characterized
Shigellosis Vaccine - Shigella porin induces expression of IgM, IgG2a, and IgA
Signal Transduction - Escherichia coli signal transduction studied, systems characterized
Signal Transduction - C-2 domain proteins studied, unusual calcium binding properties revealed
Sleep Apnea - Neuropeptide Y increased in patients with obstructive sleep apnea
Sleep Research - Serotonergic dorsal raphe neurons analyzed, effects of orexins revealed
Sleeping Sickness - Newly discovered protein an important tool for sleeping sickness research
Smooth Muscles - Motilin receptors analyzed, related signaling pathways clarified
Staphylococcus Vaccine - Mutant staphylococcal enterotoxin protects against infection
Stem Cell Research - CD38 expressed in myeloblast nuclei during RA-induced differentiation
Stem Cell Research - CTGF regulated by Wnt and BMP signaling in MSC osteoblast differentiation
Stem Cells - Study finds hematopoietic stem cells depend on a single protein Mcl-1
Synaptic Transmissions - Protein expression analyzed, correlation with transmitter release shown
Thyrotropin Receptors - Thyrotropin receptor studied, G protein structural determinants revealed
Tissue Engineering - Tiny flies could help reveal potential for nonembryonic stem cells
Toxicology - BPA increases serum thyroxine, alters gene expression in developing rat brain
Toxoplasmosis Vaccine - Toxoplasma gondii proteins protect against oral infection
Transcription Factors - Transcriptional repression studied, role of Sp3 sumoylation determined
Transcriptional Repressors - E2F6 complex analyzed, proliferation-specific EZH2 interaction shown
Tuberculosis Vaccines - Findings in tuberculosis vaccines provide new insights
Ubiquitin - Thermodynamic stability of ubiquitin studied, influence of alpha-helix revealed
Urology - Research in urology provides new insights
Vaccine Delivery - Fusogenic liposome used as vaccine carrier to induce CTL response
Vaccine Development - Clinical-stage pharma reports on anticancer progress at angiogenesis symposium
Vaccine Development - Toll-like receptors induce antigen cross-presentation
Vaccine Development - Virus-like particles as carriers for T-cell epitopes investigated
Vaccinia Virus - Vaccinia virus protein functions at mitochondria to inhibit apoptosis
Vascular Smooth Muscles - Contraction of vascular smooth muscle studied, role of ERK1/2 clarified
Vascular Smooth Muscles - Vascular smooth muscle cell motility studied, influence of STAT-3 revealed
Vector Development - Cationic polypeptides help neurons attract gene therapy
Vector Development - Epstein Barr-based plasmid vector and emulsion complex improves gene expression
Vector Development - Microarray investigates virus vector-related changes after transfection
Virology - Findings advance knowledge in virology research
Virology - Swine vesicular disease virus analyzed, importance of arginine 20 revealed
Virology Vaccine - Viral DNA-binding domain elicits anti-DNA antibodies
Wound Care - Upregulated cardiac ankyrin repeat protein accelerates wound healing
X Inactivation - X inactivation studied, boundaries between chromosomal domains clarified
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