Published in Proteomics Weekly, April 11th, 2005
"Recent studies have shown an increased expression of several MMP during cardiac, renal and pulmonary allograft rejection. To further define the roles of MMP-2 and MMP-9 in the pathogenesis of cardiac allograft rejection, BALB/c cardiac allografts were transplanted into MMP-2-deficient (-/-) and MMP-9(-/-) mice," wrote L.G. Campbell and colleagues, Washington University.
"Allografts rejected by wild-type mice revealed a significant increase in MMP-2 and MMP-9 expression. MMP-2-deficiency...
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