Published in Proteomics Weekly, May 30th, 2005
"Erythropoietin, the principal regulator of erythroid progenitor cells, also promotes neuronal survival. Using primary cultures of rat hippocampal neurons, we investigated whether erythropoietin could mediate neuroprotection favoring the transcription of BDNF," wrote B. Viviani and colleagues, University of Milan.
"Erythropoietin (2.7 nM) reduced by approximately 50% the neuronal death triggered by the prototypic neurotoxicant trimethyltin (TMT) and time-dependently induced BDNF mRNA....
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