Disease Associations

Porphyromonas gingivalis examined, periodontal fimA genotypes clarified

Published in Proteomics Weekly, May 30th, 2005

A study from Japan has chronicled the prevalence and pathogenic differences of Porphyromonas gingivalis fimA genotypes in patients with aggressive periodontitis.

"The fimA gene, which encodes fimbrillin (FimA), is found in P. gingivalis and has been classified into six genotypes based on nucleotide sequence. P. gingivalis that possesses the type II fimA gene is prevalent in adult periodontitis. The aim of this study was to investigate the prevalence of P. gingivalis fimA genotypes in Japanese aggressive periodontitis patients, and to examine their virulence," wrote M. Miura and colleagues, Kyushu University.

"Subgingival...

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Source: Proteomics Weekly (2005-05-30)

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