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Disease Associations

Salmonella studied, influence of kinesin recruitment defined

Published in Proteomics Weekly, July 4th, 2005

According to recent research from France, the intracellular fate of Salmonella depends on the recruitment of kinesin.

"Salmonella enterica causes a variety of diseases, including gastroenteritis and typhoid fever. The success of this pathogen depends on its capacity to proliferate within host cells in a membrane-bound compartment."

"We found that the Salmonella-containing vacuole recruited the plus-end-directed motor kinesin. Bacterial effector proteins translocated into the host cell by a type III secretion system antagonistically regulated this event," wrote E. Boucrot and colleagues, University of Mediterranee.

"Among...

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