Spinal Cord Injury

Spinal cord development and injury studied, connexin expression clarified

Published in Proteomics Weekly, August 29th, 2005

Recent research from Sweden has documented glial and neuronal connexin expression patterns in the rat spinal cord during development and following injury.

"Spinal cord injury induces a complex cascade of degenerative and remodeling events evolving over time. The possible roles of changed intercellular communication via gap junctions after spinal cord injury (SCI) have remained relatively unexplored.

"We investigated the temporospatial expression patterns of gap junctional genes and proteins, connexin 43 (Cx43), Cx36, and Cx32, by in situ hybridization and immunohistochemistry in the rat neonatal, adult normal, and adult injured spinal cord," wrote...

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Source: Proteomics Weekly (2005-08-29)

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