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Ovarian Cancer

Study declares new markers of ovarian cancer be judged against CA125

Published in Proteomics Weekly, November 7th, 2005

A recent study declares that new markers of ovarian cancer shoulg be judged against CA125.

Researchers in Ireland reported, "CA125 is currently the most widely used tumor marker for ovarian epithelial cancer. The aim of the article by "M. J. Duffy and colleagues, St. Vincents Hospital, "was to provide guidelines for the routine clinical use of CA125 in patients with ovarian cancer."

"Due to lack of sensitivity for stage I disease and lack of specificity, CA125 is of little value in the detection of early ovarian cancer," explained the scientists. "At present, therefore, CA125, either alone or in combination with other modalities, cannot be...

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