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Proteomics Weekly

Susan Hasty, Publisher

Table of Contents . . . January 30th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Proteomics Weekly | Other Publications

Gene Expression - Data-mining technique strikes genetic gold

Hepatocellular Cancer - Heat-shock protein 27 is a potential biomarker for hepatocellular carcinoma

Acetaminophen - Celecoxib treatment alters normal fracture healing in rats, acetaminophen treatment does not

Addiction Medicine - Gene transfer of GLT-1 attenuates morphine-induced place preference in rats

Adenoid Cystic Cancer - Expression of galectin-3 implicated in adenoid cystic carcinoma

Allergy & Immunology - Peptide-based vaccination for allergies was focus of review

Alzheimer Disease - Altered brain activity can be indicator of Alzheimer risk

Alzheimer Disease - Cell-derived oligomers of A-beta show promise for Alzheimer therapy

Alzheimer Disease - Model-guided microarray analysis identifies pathological role for retromer complex

Alzheimer Disease - New animal study links Alzheimer disease to abnormal cell division

Alzheimer Disease - Review examines immunotherapy for Alzheimer disease and other dementias

Amyotrophic Lateral Sclerosis - Researchers uncover new toxic mechanism in amyotrophic lateral sclerosis

Anesthesia - Nitrous oxide is first inhalational anesthetic without preconditioning effect

Angiology - New data illuminates research in angiology

Angiology - Novel method facilitates isolation of microvascular endothelial cells from mouse skin

Antibiotics - SXN motif of PBP 5 appears intimately involved in catalytic mechanism of deacylation

Antibody Microarrays - Epoxy-silane enhanced surface slides with glycerol provide optimal substrate

Antisense Technology - Antisense treatment influences E-cadherin in human gastric carcinoma cells

Antisense Technology - Protein expression following chronic morphine is regulated by spinal glucocorticoid receptor

Apoptosis - Alcohol stimulates activated hepatic apoptosis in genetically obese mice

Apoptosis - Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E

Apoptosis - Bile duct ligation exerts antiapoptotic effects

Apoptosis - FGF1 inhibited p53-dependent apoptosis and cell cycle arrest

Apoptosis - Human hepatitis B virus X protein induces apoptosis in HepG2 cells

Apoptosis - Inhibitors of arachidonic acid metabolism signal apoptosis in neoplastic cells

Apoptosis - Janus kinase-2 signaling mediates apoptosis in rat cardiomyocytes

Apoptosis - Sulforaphane induced apoptosis in human hepatoma HepG2 cells

Atherosclerosis - Fas ligand gene transfer increases vulnerability of atherosclerosis

Biliary Cirrhosis - Asymmetric dimethylarginine functions in biliary cirrhosis pathophysiology

Biomaterials - Scientists discover new technique for protein crystallization

Biomedical Engineering - Life science high tech company introduces integrated lysis, affinity purification columns

Biotechnology - Researchers express the potential of transgenes from insects to develop disease resistant crops

Brain Cancer - Key receptor involved in glioblastoma is identified

Breast Cancer - CD24 expression was associated with tumor growth and metastasis

Breast Cancer - Cyclin E overexpression transactivates expression of calpain 2

Breast Cancer - Drugs that suppress angiogenesis and hormonal activity may help faslodex overcome drug resistance

Breast Cancer - Expression levels of LIV-1 were associated with better outcome in breast cancer

Breast Cancer - Findings in breast cancer provide new insights

Breast Cancer - Mitochondrial and glycolytic proteome alterations linked to prognosis of breast cancer

Breast Cancer - Proteomic profiling technology may enable validation of breast cancer biomarkers

Breast Cancer - Researchers describe findings in breast cancer studies

Breast Cancer - Validation of serum biomarkers can help determine broader use of candidate markers

Brucellosis Vaccine - Outer membrane protein 31 protects against Brucella melitensis

Business & Finance - Biotech company divests cell line evolution service business to Invitrogen Corporation

Cancer Cell Biology - Interleukin-9 is expressed in nasal natural killer/T-cell lymphoma cell lines

Cancer Gene Therapy - Novel oncolytic adenovirus targets tumor-associated polo-like kinase 1

Cancer Gene Therapy - Oral adeno-associated virus-sTRAIL gene therapy suppresses hepatocellular carcinoma

Cancer Research - Octamer binding transcription factor Oct-1 acts as a stress sensor

Cancer Therapy - A new fusion toxin targets angiogenic factors in bladder tumors

Cancer Therapy - Angiogenin propels prostate cancer progression

Cancer Therapy - Growth factor receptor signaling promotes non-small cell lung cancer tumor survival

Cancer Therapy - Interferon signaling pathways are modulated by interleukin-12

Cancer Therapy - Multidomain approach used to enhance tumor selectivity of macromolecules

Cancer Therapy - Remodeling of heparan sulfate proteoglycans shown as potential cancer therapy

Cancer Therapy - Reports describe recent advances in cancer therapy research

Cancer Vaccine - Antitumor effects of CTLA-4 blockade are caused by increased T cell activation

Cancer Vaccine - CTLs cross-react with O-glycosylated and non-glycosylated MUC1-derived peptides

Cancer Vaccine - CpG ODN act through TLR9 to enhance NK cell cytokine response to tumor cells

Cancer Vaccine - Dendritic cell maturation in presence of prostaglandin E-2 optimizes responses to protein antigens

Cancer Vaccine - Report describes computational modeling of the immune response to tumor antigens

Cancer Vaccine - Telomerase vaccine does not affect colony-forming in bone marrow of cancer patients

Cancer Vaccines - Research in cancer vaccines provides new insights

Carcinogenesis - Centrosome amplification, chromosome instability and cancer development examined

Cardiovascular Disease - CD40/CD40L balance may be lost in patients with unstable angina

Cardiovascular Research - Review examines developments in ghrelin biology and clinical relevance

Cell Biology - First clear molecular images reveal structure of Dicer enzyme

Cervical Cancer - Reports add new data to cervical cancer research

Cervical Cancer Vaccine - Vaccine based on live lactococci protects against HPV-induced tumors

Chemotherapy - MDR1 locus displays epigenetic changes in response to chemotherapeutic drugs

Cholangiocarcinoma - Reduced immunoexpression of E-cadherin and FAT linked to cholangiocarcinogenesis

Chondrosarcoma - Antiestrogen therapy proposed as treatment option of chondrosarcoma

Chronic Liver Disease - Leptin upregulates proinflammatory and proangiogenic cytokines in liver cells

Clinical Trials - Biopharm company to focus on small-molecule drugs for Crohn, rheumatoid arthritis in 2006

Clinical Trials - Phase 1 studies' results with agonist for GT motility dysfunction show prokinetic effect

Collaborations - Biosciences company announces expansion of research collaboration agreement with Pfizer Inc

Collaborations - Collaboration inked for trial for the treatment of critical limb ischemia with VEGF-2

Collaborations - Deal signed with Idenix for development of antiviral therapies

Collaborations - Harvard Medical School and nanotechnology company to collaborate on a new protein biochip

Complementary & Alternative Medicine - Black tea and theaflavin induced apoptosis in human leukemia cells

Complementary & Alternative Medicine - Homeopathic arsenic remedy Arsenicum Album-30 shows promise in combating arsenic poisoning

Contact Sensitivity - Peritoneal B-1 cells migrate to lymphoid organs one hour after immunization

Cystic Fibrosis - Researchers' work adds to cystic fibrosis body of knowledge

Cystic Fibrosis - Wild-type CFTR maintains biosynthetic/secretory integrity in pancreatic duct cells

DNA Research - Cationic liposomes permit naked plasmid DNA uptake in human macrophages

DNA Research - Reporter gene dilution does not alter polyethylenimine transfection efficiency

Dendritic Cell Vaccine - Cell surface recycling of internalized antigen permits B cell priming

Dental Surgery - Recombinant bone morphogenetic protein induces maxillary sinus bone induction

Developmental Biology - Hematopoietic stem cells can be identified early in zebrafish embryo development

Developmental Biology - Maternal Xenopus negatively regulates nodal-related gene expression

Developmental Biology - POPK-1/Sad-1 kinase is required for translocation in the ascidian embryo

Diabetes Complications - Contractile responses to angiotensin peptides are enhanced in diabetic clitoral cavernosum

Diabetes Complications - Endothelin-1 JAK2 activation in VSMCs involves NAD(P)H oxidase-derived reactive oxygen species

Diabetes Diagnosis - Elevated ALT and GGT levels are independent predictors of high diabetes risk in older men

Diabetes Epidemiology - Pro12Ala variant in PPARG influences susceptibility to type 2 diabetes

Diabetes Pathogenesis - Arachidonic acid inhibits insulin glucose-6-phosphate dehydrogenase induction via p38 MAPK

Diabetes Pathogenesis - Dystrophin-dystroglycan and syntrophin-nNOS complex may control insulin resistance in muscle

Diabetes Pathogenesis - ERK is needed for IL-1-induced and NFkappaB-mediated gene expression in INS-1E cells

Diabetes Pathogenesis - Hypoglutathionemia is linked to reduced Na+/K+ ATPase activity in type 2 diabetics

Diabetes Pathogenesis - Inflammatory mediators by abdominal adipose tissue may link obesity and insulin resistance

Diabetes Pathogenesis - Study explores isoform expression in adipocytes and their function in metabolic regulation

Diabetes Research - Bosentan improves vascular reactivity in diabetic rats, but not by changing PKC isoforms

Diabetes Research - Study finds two ARBs as SPPARMs that may be cardiovascular disease and diabetes targets

Diabetes Risk Factors - Ethanol feeding decreased insulin-dependent glucose through Cbl/TC10 pathway dysregulation

Diagnostics - Angiogenic protein with dinucleotide mutations may identify select colorectal cancers

Diagnostics - EGFR tyrosine kinase inhibitors screened as potential tumor imaging probes

Diagnostics - Enzyme metallography useful for high-resolution immunophenotyping

Diagnostics - Microarrays based on GCSPR may facilitate cell and protein analysis

Diagnostics - More than one biomarker needed for early diagnosis, evaluation of neurodegenerative disease

Drug Delivery - Researchers' work adds to drug delivery body of knowledge

Drug Development - Type IV pili-binding peptide R inhibits Salmonella Typhi infection

Drug Development - U.S. FDA approves abatacept compound for treatment of rheumatoid arthritis

Drug Resistance - A pleiotropic drug resistance transporter in yeasts has narrower substrate specificity

Drug Resistance - Cancer resistance to chemotherapy linked to longevity gene sirt1

Drug Resistance - Study indicates limited genetic diversity in Plasmodium falciparum parasites from Suriname

Enterobacter Diagnosis - Method is developed to differentiate thermal-resistant strains of Enterobacter sakazakii

Enterovirus - Research investigated recombination in circulating human enterovirus B

Enzymology - PECAM-1 may initiate a receptor-mediated pathway triggering human sperm capacitation

Enzymology - Research in enzymology provides new insights

Enzymology - The thrombin peptide TP508 generates early angiogenic sprouting

Epithelial Cancer - BetaV-tubulin expressed in human tumor cell lines

Erythropoiesis - TNF superfamily members contribute to mediated inhibition of erythropoiesis

Fabry Disease Therapy - Agalsidase-beta is approved for treatment of Fabry disease

Fitness & Wellness - Endurance training raises muscle LKB1 and PGC-1 alpha protein levels similar to citrate synthase

Fitness & Wellness - Exercise induces changed gene expression of 5'-AMP-activated protein kinase

Gastric Cancer - Loss of Fhit expression holds no clinical value in gastric cancer

Gastrointestinal Adenocarcinoma - Cancer procoagulant cited as risk factor for thrombosis in gastric cancer patients

Gastrointestinal Tumors - IQ motif protein may serve as a diagnostic marker for gastrointestinal tumors

Gene Expression - Research explores code for control of gene expression

Gene Research - A genome-wide RNA interference screen detects Hh signaling pathway components

Gene Research - Involvement of E2F transcription factor family in cancer reviewed

Gene Research - Oncoprotein suppresses p53 activation via gene expression mechanism

Gene Therapy - Biochemical properties of hamartin and tuberin described

Gene Therapy - Cell-permeable HBV-like particles allow efficient gene transfer into hepatocytes

Gene Therapy - Engineered T lymphocytes resist cytokine withdrawal-induced apoptosis

Genetics & Genomics - Beta-blockers may inhibit collagen-related gene expression

Genetics & Genomics - British research institute announces US$604 million in new funding from Wellcome Trust

Genetics & Genomics - Genetic variation in the gly1619arg SNP of the IGF2R gene is linked to childhood height

Genetics & Genomics - Jab1 identified as possible target for 8q gain via array-based CGH analysis

Genetics & Genomics - Scientists determine how Plasmodium falciparum uses cloaking genes

Genetics & Genomics - Smoking induces consistent and distinctive pattern of alveolar macrophage activation

Glioma - CD155/PVR promoted glioma cell migration

Gynecology - Macrophage migration inhibitory factor displays cyclical expression in the endometrium

HIV/AIDS Genetics & Genomics - Novel HIV-1 circulating AIDG intersubtype recombinant form is identified in Cuba

HIV/AIDS Vaccine - Multi-envelope HIV vaccine devoid of SIV components controls SHIV

HIV/AIDS Vaccine - Review examines the virology of HIV-1 and its replication

HIV/AIDS Vaccines - Reports advance knowledge in HIV/AIDS vaccines research

Heart Failure - Urocortin 2 may offer therapeutic benefit in heart failure

Hepatitis B Virus - Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients

Hepatitis B Virus - CpG oligodeoxynucleotide-activated mononuclear cells display anti-HBV effects

Hepatitis B Virus - Hepatitis B virus replication is inhibited by various RNAi constructs

Hepatitis B Virus - Loss of HBV DNA after seroconversion alters virological characteristics

Hepatitis C Vaccine - Researchers in Canada develop dendritic cell-based therapeutic vaccine

Hepatitis C Virus - HCV glycoprotein assembly on infectious pseudoparticles occurs intracellularly

Hepatitis C Virus - Hepatitis C structural proteins induce interleukin 8 production and apoptosis

Hepatitis C Virus - Hepatitis C virus RNA can be partially reconstructed in bacterial cells

Hepatitis C Virus - Hepatitis C virus populations vary in HIV/HCV-co-infected patients

Hepatitis C Virus - Interferon-neutralizing antibodies are detectable in chronic hepatitis C

Hepatitis C Virus - Sustained E2 antibody response correlates with reduced peak viremia after HCV infection

Hepatocellular Cancer - Conditionally replicative adenovirus vectors facilitate enhanced hepatocellular carcinoma oncolysis

Herpes Vaccine - Live attenuated herpes type 2 vaccine shows promise in guinea pigs

Huntington Disease - New research in the area of Huntington disease detailed

Imaging - Researchers report details of new studies and findings in the area of imaging

Imaging - SPR imaging-based arrays suitable for screening protein-protein interaction inhibitors

Immune Modulation - Data appears to support HO-1-targeted therapy for immune modulation

Immunology - CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells

Immunology - Family of bacterial proteins involved in gastrointestinal diseases identified

Immunology - Interphotoreceptor retinoid-binding protein epitope is recognized by autoreactive T cells

Inflammatory Bowel Disease - A circulating soluble IL-6 receptor component may inhibit IL-6

Interleukin-12 - Functional IL-12 from mouse is expressed in transgenic tomato plants

Kidney Disease - Lipid marker predicts progressive loss of renal function

Leukemia - Decreased expression of C/EBP zeta associated with leukemia

Leukemia - Intensified induction therapy used to treat FLT3/ITD+ leukemia patients

Leukemia - PARP-1 down-modulation in leukemia cells restores transcriptional responsiveness

Listeria Vaccine - Membrane TNF confers partial protection to Listeria infection

Liver Disease - Serum nuclear matrix protein levels are diagnostic of organ damage in liver disease

Liver Function - B13 progenitor cell model aids study of liver function

Liver Injury - Induced liver injury is mediated by tumor necrosis factor independent of Kupffer cells

Lung Cancer - CYP1A1 and CYP1B1 polymorphisms linked to lung cancer risk

Lung Cancer - Estrogen receptor hypermethylation associated with lung tumorigenesis

Lung Cancer - Gefitinib and inhibitors of P13K/Akt and Ras/Erk pathways used in lung cancer

Lung Cancer - Interactome-transcriptome analysis useful for identifying key genes

Matrix Metalloproteinase - Ligand interactions and substrate specificities overlap in MMP-9 and -2

Matrix Metalloproteinase - MMP-8-deficient mice are resistant to induced lethal hepatitis

Medical Devices - IDE filed with U.S. FDA for plasma delipidation system to remove HDL from human blood

Melanoma - Gastrin impacts melanoma cells in a pleiotropic fashion

Melanoma - High serum galectin-3 implicated in advanced melanoma progression

Melanoma - Levels of soluble adhesion molecules used to prognosticate malignant melanoma

Melanoma - SPARC and GPC3 identified as possible tumor markers, especially for melanoma

Melanoma - Vascular endothelial growth factor loop promotes melanoma cell invasiveness

Melanoma Vaccine - CD28-mediated costimulation affects differentiation of vaccine-induced T cell responses

Melanoma Vaccine - GM-CSF converts autoimmune response to self-antigen into antitumor response

Mergers & Acquisitions - Bioprocessing services company sells New Jersey operation to Discovery Lab for $16 million

Mergers & Acquisitions - Fine chemicals company acquires peptide resin technology from Colorado Biotechnology

Muscular Dystrophy - Aggregation of expansion mutant of PABPN1 in HeLa cells is reduced by HSP70

Mycobacterium Tuberculosis -  M. tuberculosis PtpB structure reveals diverged fold and buried active site

Myeloma - Growth factors and antiapoptotic signaling pathways in multiple myeloma analyzed

Myocardial Infarction - Hypoxia-inducible factor 1-alpha improves cardiac health in heart attack models

Myocardial Infarction - Recombinant human erythropoietin extends cardioprotection following myocardial infarction

Natural Products - Morin affects snake venom phospholipase by modifying aromatic amino acids

Neuroblastoma - Caspase 8/10 did not mediate apoptosis in neuroblastoma cells treated with CDK

Neurodegeneration - Vascular remodeling guides cerebral dysfunction in patients with Alzheimer disease

Neuroepithelial Tumors - New epilepsy-related clinicopathological entity classified

Neuroscience - Reports add new data to neuroscience research

Neuroscience - Synthetic 18F-labeled 4-anilidopiperidines show promise as mu-opioid receptor imaging agents

Obesity Pathogenesis - Adrenomedullin is produced mainly in adipose tissue and influences obesity development

Obesity Pathogenesis - Peptide YY secretion after oral glucose is higher in females than in males

Obesity Pathogenesis - Scientists identify protein that blocks fat production, produces more bone

Ocular Adnexal Lymphoma - BCL10 expression not correlated with outcome

Oncology - All-trans-retinoic acid ends vascular endothelial growth factor expression in rhabdomyosarcoma

Oncology - Host-secreted protein acidic and rich in cysteine dulls ovarian cancer progression

Oncology - Murine urethane models mirror key features of human lung cancer carcinogenesis

Oncology - New findings in oncology described

Oncology - Research in oncology provides new insights

Oncology - Researchers detail new studies and findings in the area of oncology

Oncology - Wnt5a makes non-small-cell lung cancer become more aggressive

Ophthalmology - Conjunctival cells may influence lymphangiogenesis during immunological insult

Ophthalmology - Nuclear protein in pro-angiogenic retinal astrocytes is regulated by oxygen levels

Ophthalmology - STAT3 may be involved in the pathogenesis of proliferative retinopathy

Ovarian Cancer - Proteomic tracking of serum proteins can enhance biomarker detection for ovarian cancer

Ovarian Cancer Vaccine - Expression of FoxP3 is linked to poor prognosis in ovarian cancer

Pancreatic Cancer - Key individual and combined serum proteins identified via antibody microarray profiling

Parkinson Disease - Gene delivery of GDNF protects nerves in rat model of Parkinson disease

Parvovirus Vaccine - Tobacco chloroplast-derived vaccine induced parvovirus neutralizing antibodies

Patents - Biotherapeutics company gets fifth U.S. patent in its phage display patent portfolio

Pediatric Obesity Pathogenesis - Peptide YY regulates energy homeostasis in obese children before and after weight loss

Pharmaceutical Research - Hypericin-photodynamic therapy and COX-2 inhibitor control angiogenesis in nasopharyngeal tumors

Pharmaceutical Research - Mechanism of formation of T cells' actin filaments described

Pharmaceutical Research - Poxvirus protein finding could lead to treatment for inflammatory diseases

Plant Genomics - XanB2 may play a role in the biosynthesis of DF

Pneumococcal Vaccine - Pneumococcal conjugate vaccine induced functionally active antibodies in infants

Pneumococcal Vaccines - Studies describe new findings in pneumococcal vaccines research

Preterm Birth - Review examines genetic variation associated with preterm birth

Product Licensing - Biopharma company provides nonexclusive licenses to Merck for humanized antibodies

Prostate Cancer - Decreased annexin I expression used to prognosticate prostatic adenocarcinoma

Prostate Cancer - Doxazosin appears to induces apoptosis in prostate cancer cells through a novel mechanism

Prostate Cancer - Genetic and proteomic profiling of prostate cancer predicted clinical outcome

Prostate Cancer - Hydrogen peroxide boosts proliferation and migration of prostate cancer cells

Prostate Cancer Vaccine - Report presents map of PSMA epitopes recognized by antibodies induced by gene-based vaccines

Protein Production - Cell-free synthesis of proteins is achieved at productivity comparable to plasmid-based reactions

Proteomics - Findings advance knowledge in proteomics research

Proteomics - GPRC6A reported to be a cation-, calcimimetic, and osteocalcin-sensing receptor

Proteomics - Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis

Proteomics - Novel design facilitates study of chromogranin A antigenic sites

Proteomics - Novel microchip electrophoresis system devised for rapid lipoprotein analysis

Proteomics - Pharmaceutical company inks oncology target licensing agreement with ImClone

Proteomics - Reports advance knowledge in proteomics research

Proteomics - Tissue microarray analysis of activator protein-2 alpha subcellular expression can predict outcome

Pulmonary Adenocarcinoma - CD44 splicing pattern associated with disease progression in adenocarcinoma

Pulmonary Fibrosis - Pulmonary fibrosis is adenosine dependent in adenosine deaminase-deficient mice

Pulmonary Medicine - Oxidative stress may lower VEGF levels to promote chronic obstructive pulmonary disease

Reproductive Biology - Beta-defensin 126 on cell surface protects sperm from immunorecognition

Retrovirus Therapy - CpG ODN effectively treat retrovirus-induced antibody suppression

SARS Vaccines - New findings in the area of SARS vaccines described

Schistosomiasis - New research in the area of schistosomiasis detailed

Scleroderma - Integrin alphav beta3 is a target for treatment of scleroderma

Smallpox Vaccine - Diversity is found in acute CD8 T cell response to vaccinia virus

Smallpox Vaccine - Positive results of synDNA smallpox vaccine study announced

Spindle Cell Cancer - Mucinous tubular and spindle cell carcinoma described

Squamous Cell Carcinoma - Cyclooxygenase-2 was overexpressed in Chinese esophageal squamous cell carcinoma

Squamous Cell Carcinoma - DIF-1 inhibited gene expression of cyclin D1 in tumor cells

Squamous Cell Carcinoma - Fas/Fas-L expression used in tumor grading of oral squamous cell carcinomas

Stroke - Data advance knowledge in stroke research

Systemic Lupus Erythematosus - Cytomegalovirus protein is humoral immunogen for lupus patients

T Cells - Alloreactive populations comprise subsets of T cells

Tobacco Use - Nrf2 is activated by aqueous extracts of cigarette smoke

Tuberculosis Therapy - Point mutations in M. tuberculosis genes linked to drug resistance are identified

Tuberculosis Vaccine - Deleted genomic regions of BCG vaccine may hold key to effective TB vaccination

Tumorigenesis - Expression of JC virus regulatory proteins implicated in human cancer

Type 2 Diabetes - Differential effects of beta-blockers on albuminuria were studied in type 2 diabetics

Type 2 Diabetes - PPAR-gamma activation by rosiglitazone protects islet cells from amyloid polypeptide toxicity

Type 2 Diabetes - Researchers discover mechanistic link between high-fat diet and type 2 diabetes

Vaccine Development - IgE enhances antibody and T cell responses in vivo via CD23+ B cells

Vaccine Development - Oligopeptide from HIV-1 Vpr improves gene expression in resting macrophages

Vaccine Vectors - Adenovirus infection promotes LPS-induced TNF production and sensitizes to lethal shock

Vaccines Vector - Recent studies add new data to vaccines vector research

Vector Development - Artificial chromosome vector provides effective transgene expression

Vector Development - Reports advance knowledge in vector development research

Virology - A viral gene promoter is subject to circadian control

Virology - Cytomegalovirus encodes MHC class I-like molecule that inhibits NK cell lysis

Virology - GB virus C infection is associated with a reduced HIV load

Virology - Research add new data to virology body of knowledge

Virology Vaccine - CXCR5-dependent seeding of follicular niches augments antiviral B cell responses

Virology Vaccine - Studies explore molecular and cellular bases of retrovirus resistance in I/LnJ mice

Virology Vaccine - TLR-mediated induction of IFN is redundant for protective immunity to viruses

Von Willebrand Disease - A variant of a von Willebrand factor gene is defective in collagen binding

Wound Healing - Keratinocyte growth factor is vital for accelerated wound healing

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