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Proteomics Weekly

Susan Hasty, Publisher

Table of Contents . . . April 24th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Proteomics Weekly | Other Publications

Aspergillosis -  Aspergillus fumigatus proteome characterized through novel approach

Cardiomyocytes - Heart failure is rescued by calstabin2 in mice

Diagnostics - Proteomic screening leads to early detection of acute GVHD after stem cell transplantation

Hepatitis B Virus - Recombinant GB virus B hepatitis virus with a p7 protein developed

Proteomics - Lung cancer CPT-11/SN-38 resistance marked by ABCG2 expression

Acute Hepatitis - In acute hepatitis, glycoprotein oligosaccharides are modified by reactive oxygen species

Acute Promyelocytic Leukemia - All-trans retinoic acid molecular effects in acute promyelocytic leukemia elucidated

Adverse Drug Reaction - Gefitinib-induced interstitial lung disease is identified by serum markers

Allergy & Immunology - Aspirin-triggered lipoxin anti-inflammatory activity is SOCS-2 dependent

Alzheimer Disease - Alzheimer disease amyloid plaque suppressed by marrow-derived microglia

Alzheimer Disease - Targeting A-beta oligomers improves learning and memory

Angiology - Clopidogrel withdrawal is linked to proinflammatory and prothrombotic effects in diabetes

Angiology - Concerning mediators of endothelial function and their clinical relevance, information is scant

Angiology - In coronary heart disease, inflammation enhances endothelial tissue plasminogen activator release

Angiology - In stable angina, inflammation marker hs-CRP and complement activation marker C3a are elevated

Angiology - Postnatal angiogenesis is guided by EphB4

Angiology - Research in angiology provides new insights

Anthrax Vaccine - N-fragment of edema factor is candidate antigen for anthrax vaccine

Anthrax Vaccine - Persistence of immunity following anthrax vaccination was examined

Antimicrobial Agents - Degenerate phosphorothioate oligonucleotides prevent prion conversion

Apoptosis - Apoptosis is regulated by peptides of fibronectin in human monocytes

Apoptosis - Apoptosis repressor with caspase recruitment domain is required for post-ischemia cardioprotection

Apoptosis - Cardiomyocyte apoptosis is prevented by Trypanosoma cruzi infection and NF kappa-B activation

Apoptosis - Osteosarcoma apoptosis induced by alpha-Tocopheryl succinate

Apoptosis - Tumor cell resistance to effector mechanisms of cytotoxic lymphocytes discussed

Arterial Thrombosis - Targeting PAR1-PAR4 may offer opportunity to prevent arterial thrombosis

Arthritis - Findings describe new data in arthritis research

Arthritis - Rheumatoid arthritis angiogenesis is driven by interleukin-18

Astrocytomas - Clear cell primary brain tumors diagnosed by NeuN expression

Atherosclerosis - Atherosclerosis lesions may be prevented with aged garlic extract

Atherosclerosis - New research in the area of atherosclerosis detailed

Autoimmunity - Autoreactive plasma cells in spleen are present before disease onset

Avian Influenza Vaccine - Adenovirus-based vaccine protects against lethal H5N1 avian influenza

Awards - Thermo Electron Corporation receives Gold Editor's Award for mass spectrometry technology

Bacteriology - Researchers detail new studies and findings in the area of bacteriology

Bone Cancer - Osteosarcoma inhibition by meloxicam involves COX-2-dependent and independent routes

Bone Marrow - Bone marrow stromal cell proliferation and osteogenic potential is enhanced by osterix

Brain Cancer - Glioma proposed as possible target for antitumor agent perillyl alcohol

Breast Cancer - BRCA1 and FOXA1 proteins co-regulate kinase inhibitor expression

Breast Cancer - Breast cancer ER-related genes and pathways identified after laser capture microdissection

Breast Cancer - Breast cancer angiogenesis is stimulated by stromal syndecan-1

Breast Cancer - Breast cancer cells find an adenovirus cytotoxic

Breast Cancer - Breast cancer pathogenesis linked to differential expression of PTEN

Breast Cancer - Breast cancer prognosis associated with overexpression of human Kallikrein 14

Breast Cancer - Breast cancers use hypoxia inducible factor to boost angiogenesis and metastasis

Breast Cancer - Erythropoietin inhibits apoptosis in breast cancer cells without modulating chemosensitivity

Breast Cancer - HER2-overexpressing breast tumors suppressed by novel synthetic triterpenoid

Breast Cancer - Mammary tumorigenesis in mice is promoted by matrix metalloproteinases

Business & Finance - Helix BioMedix reports 2005 net loss of $3,277,239

Cancer Gene Therapy - Chemosensitivity of malignant melanomas is increased by beta gene transfer

Cancer Gene Therapy - Epigenetically silenced tumor suppressor overcomes resistance to apoptosis induction by interferons

Cancer Gene Therapy - HCC cell proliferation is inhibited via decreased telomerase activity

Cancer Gene Therapy - Virus dissemination in local gene delivery is governed by rate, volume, and dose

Cancer Prognostics - Tumor-associated lymphatic endothelial cells display CD34 exclusivity

Cancer Research - Ohio State University researchers show viral protein is needed for successful infection

Cancer Therapy - Alpha-tocopherol succinate inhibits oncogenic Ras signaling

Cancer Therapy - Angiogenesis is altered by the upstream activity of indole derivative DIM

Cancer Therapy - Congestive heart failure, renal failure and cancer treated by cardiac natriuretic peptides

Cancer Therapy - DNA methyltransferase inhibitors are angiostatic in tumors

Cancer Therapy - Findings describe new data in cancer therapy research

Cancer Therapy - G-quartet oligonucleotides target transduction and transcription in head and neck cancer

Cancer Therapy - Integrin-targeted chemotherapy may be compromised by antiangiogenic therapy

Cancer Therapy - Protein Tyr phosphatase PRL-3 functions in malignant and endothelial cells

Cancer Vaccine - Dendritic cells pulsed with tumor lysate enhance immunity in pancreatic cancer

Cancer Vaccine - Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit antitumor immunity

Cancer Vaccine - Fusion protein has pro-apoptotic activity in carcinomas overexpressing HER2

Cancer Vaccine - LAGE-1 peptide is recognized by cytolytic T lymphocytes on HLA-A68 tumors

Cancer Vaccine - Multi-epitope peptide vaccines alter CD8+ T cell responses

Cancer Vaccine - Telomerase-specific T cells kill pancreatic tumor cells

Cancer Vaccines - New data illuminates research in cancer vaccines

Cancer Vaccines - New findings in cancer vaccines described

Cancer Vaccines - Recent findings illuminate research in cancer vaccines

Cancer Vaccines - Reports describe recent advances in cancer vaccines research

Cancer Vaccines - Research add new data to cancer vaccines body of knowledge

Cancer Vaccines - Researchers' findings advance cancer vaccines research

Candidiasis - DNA probes for rapid identification of Candida species have been developed

Carcinogenesis - Carcinogen-bioactivating cytochrome is inhibited by pifithrin alpha

Cardiac Hypertrophy - Cardiac hypertrophy and myelo-lymphoproliferative disorders are caused by gene haploinsufficiency

Cardiology - Apolipoprotein infusion affects atheroma regression and change in lumen size

Cardiology - Carotid artery plaques could use angiogenesis and apoptosis intermediate modulation

Cardiology - Cellular basis for manifestations of Andersen-Tawil syndrome are examined

Cardiology - Coronary restenosis is prevented by the tyrosine kinase inhibitor SU11218

Cardiology - Researchers describe findings in cardiology studies

Cardiology - Studies advance knowledge in cardiology research

Cardiomyocytes - Ischemic preconditioning, 17 beta-estradiol may share a final common effector

Cardiovascular Disease - Therapeutic effects of xanthine oxidase inhibitors are considered in review

Cell Biology - BIG2 may have an important role in Tfn uptake and TfnR recycling

Cell Biology - HEF1 involved in cell division control

Cellular Biology - Substrate rigidity regulates the formation and maintenance of tissues

Chagas Disease - Hypervariable region of Trypanosoma helps elude immune recognition

Chagas Disease - In chronic Chagas' disease, Trypanosoma cruzi modulates memory profile of CD8+ T cells

Chronic Hepatitis - HBeAg-positive chronic hepatitis B is more responsive to entecavir than to lamivudine

Cirrhosis - Endotoxic liver damage in cirrhotic rats reduced by bosentan ET-1 blockade

Clinical Trials - Phase 2 data show antiviral drug maribavir significantly reduces CMV reactivation in transplants

Clinical Trials - Yale researchers find phenoxodiol restores sensitivity to chemotherapy in some cancer patients

Collaborations - Caprion Pharmaceuticals announces biomarker discovery collaboration with Vertex Pharmaceuticals

Collaborations - ChemDiv, Inc. and Carna Biosciences, Inc. form strategic alliance

Collaborations - Omnia Biologics and Intradigm sign deal for cGMP manufacturing services

Colon Cancer - Colon cancer protein tyrosine phosphatase kappa may be useful biomarker

Colon Cancer - Colon carcinoma prognosis linked to increase in number of adhesion proteins with altered expression

Colon Cancer - Liver metastasis has a selective response to antiangiogenic therapy

Colon Cancer - Ulcerative colitis-induced colon cancer marked by transgelin loss

Colorectal Adenocarcinoma - Colorectal adenocarcinoma linked to G274A isoform of hnRNP K protein mRNA

Colorectal Cancer - Colorectal cancer angiogenesis predicts patient outcomes

Colorectal Cancer - Colorectal cancer favorable prognosis linked to neuroendocrine differentiation and p53/BAX pathway

Colorectal Cancer - Colorectal cancer prognosis linked to indoleamine 2,3-dioxygenase expression

Colorectal Cancer - Colorectal cancer risk linked to serum C-reactive protein levels

Colorectal Cancer - Colorectal cell-induced apoptosis involves c-Abl-independent p73 stabilization

Contraceptive Vaccine - DNA vaccine expressing brLDH-C4' possesses anti-fertility effects

DNA Research - Cancer cell DNA methyltransferase inhibitors display functional diversity

DNA Research - CytoGenix receives first order for synDNA

DNA Research - Fibrinogen peptide resolution is increased by G-quartet DNA stationary phase destabilization

DNA Vaccine - CTLA-4-mediated targeting and CpG motifs enhance immunogenicity of DNA vaccines

DNA Vaccine - DNA vaccination elicits anti-HBV immune responses in rhesus macaques

Dermatology - Cholinergic drugs may be a promising approach for cutaneous blistering disorders

Developmental Biology - In vitro oocyte maturation requires study of epigenetic safety

Developmental Biology - Microtubules are regulated by a chromokinesin during spindle assembly

Developmental Biology - Renal tubular epithelial cell connective tissue growth factor is induced by dexamethasone

Diabetes Complications - Amadori products may play a role in the development of diabetic heart disease

Diabetes Complications - Diabetic retinopathy can be detected by serum anti-aldolase autoantibody

Diabetes Complications - InsR signaling in diabetes-impaired wounds is sensitive to inflammatory conditions

Diabetes Epidemiology - Amino acid variants in activating transcription factor 6 gene linked to type 2 diabetes

Diabetes Pathogenesis - Diminished PKC isoenzymes levels influence lead to disturbed insulin secretion in GK rat

Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research

Diabetes Pathogenesis - Increased pp38MAPK and pHSP25 comprise acute adaptation to glycemic stress in diabetes

Diabetes Pathogenesis - Metabolic syndrome traits in families may be linked to pleiotropic gene effects or environment

Diabetes Pathogenesis - Minimal breast-feeding and early cow milk/late gluten introduction raises diabetes risk

Diabetes Pathogenesis - Protein tyrosine phosphatase-N1 variants are linked to coronary calcified plaque in diabetes

Diabetes Pathogenesis - Relationship between reduced antioxidant status and insulin resistance state observed in nonobese children

Diabetes Pathogenesis - Researchers' work adds to diabetes pathogenesis body of knowledge

Diabetes Pathogenesis - alpha1 -Adrenoceptors cause glucose uptake by mediating AMPK activation in muscle cells

Diabetes Therapy - Findings advance knowledge in diabetes therapy research

Diabetes Therapy - Glucose-dependent insulinotropic peptides are long-acting stable analogues for diabetes therapy

Diabetes Therapy - Incretin mimetics and dipeptidyl peptidase-IV inhibitors offer new type 2 diabetes therapies

Diabetes Therapy - Researchers detail new studies and findings in the area of diabetes therapy

Diabetes Therapy - Researchers' data advance diabetes therapy research

Diabetic Neuropathy - Nerve growth factor delays nociceptive deficits in diabetic neuropathy model

Diagnostics - Foundation for Innovative New Diagnostics reaches second milestone in rapid TB test development

Diagnostics - MRI contrast agent relaxation affected by serum albumin levels

Diagnostics - Modified ELISA detects and quantifies heparanase

Diagnostics - Myeloma screening with turbidimetric immunoassays has limited value

Diagnostics - Serum proteomic fingerprints identify SARS cases early during onset

Diet & Nutrition - Casitas b-lineage lymphoma-deficient mice protected against obesity and diabetes

Diet & Nutrition - Cranberry juice consumption did not alter antioxidant or lipid status in healthy subjects

Drug Development - Anthracycline prodrugs used in cancer chemotherapy reviewed

Drug Development - Molecular library profiling technique may improve drug discovery

Drug Development - Nitric oxide-donating aspirin is focus of review of pharmacological and clinical perspectives

Drug Development - Tumor angiogenesis collapses in the presence of fibulins 3 and 5

Endocrinology - Proopiomelanocortin neurons in hypothalamus may mediate leptin signaling via POMC-derived peptides

Endothelial Cells - Sphingosine 1-phosphate receptors mediate expression of endothelial cell adhesion molecules

Enzymology - Vaccinia virus glycosylase forms heterodimeric processivity factor for viral DNA polymerase

Epilepsy Therapy - Brain tumor-related epilepsy resistance not due to blood-brain barrier BCRP

Esophageal Cancer - Esophageal carcinoma poor prognosis linked to activated NF-kappa B

Ewing Sarcoma - Ewing sarcoma translocation detected by RT-PCR

Fibrinogen - Fibrinogen binding of synthetic B knobs changes the character of fibrin

Finance - Dyadic reports 35% increase in R&D expenses in 2005

Finance - Sequenom reports revenues for fourth quarter of $4.4 million

Gastritis - Vaccine prevents Helicobacter pylori-induced alterations of gastric flora

Gastrointestinal Carcinomas - Gastrointestinal carcinoma prognosis linked to plasminogen activator activity

Gene Research - Cysteine cathepsin genes regulate specific stages of tumorigenesis

Gene Research - Genetic polymorphisms do not influence enzyme activity in cancer cell lines

Gene Transfer - Human periodontal ligament fibroblasts are immortalized by SV40T-antigen and hTERT gene transfer

Genetics & Genomics - Arrhythmogenic right ventricular cardiomyopathy is linked to mutations in desmoglein-2 gene

Genetics & Genomics - Cardiovascular disease studied in Hutchinson-Gilford progeria syndrome transgenic mouse model

Genetics & Genomics - Complete L segment coding-region of CCHF virus strains amplified

Genetics & Genomics - In familial hypercholesterolemia, LDL receptor mutations show heterogeneity

Genetics & Genomics - Integrated Genomics, Danone sign 3-year license for database, genomic discovery system

Genetics & Genomics - Lipoprotein lipase gene variation influences exercise-induced left ventricular growth

Genetics & Genomics - Melanocortin-4 receptor gene was not related to complications after gastric banding

Genetics & Genomics - Protein kinase C delta functions in gene expression in human monocytes

Genetics & Genomics - Sequenom reports molecular diagnostic studies using DNA analysis platform completed

Gestational Diabetes - Gestational diabetes and autoantibodies may predict women at risk for long-term diabetes

HIV/AIDS Opportunistic Infections -  Pseudomonas aeruginosa ExoU long-term cytotoxicity linked to oxidative stress

HIV/AIDS Pathogenesis - HIV Vif and Vpr play key roles in T cell death and cell cycle arrest

HIV/AIDS Therapy - Efavirenz effects on HIV reverse transcriptase subunits characterized

HIV/AIDS Therapy - Integrase cofactor plays key role in HIV replication cycle

HIV/AIDS Vaccines - Research add new data to HIV/AIDS vaccines body of knowledge

HIV/AIDS Vaccines - Researchers' data advance HIV/AIDS vaccines research

HIV/AIDS Vaccines - Studies add new findings to HIV/AIDS vaccines body of knowledge

Head & Neck Cancer - Findings describe new data in head & neck cancer research

Head & Neck Cancer - Tongue cancer invasion shows marked correlation with vascular endothelial growth factor

Heart Transplantation - Diastolic dysfunction in human cardiac allografts is related to reduced SERCA2a gene expression

Heat Shock Proteins - Heat shock protein 90 regulates activation in Sendai virus-infected cells

Hematology - Ethanol reduces thrombin-induced platelet aggregation by blocking Ca2+ entry

Hepatitis B Virus - Anti-hepatitis B virus activity and cross-resistance profile characterized

Hepatitis B Virus - HBeAg-negative chronic hepatitis B lamivudine monotherapy outcome predicted

Hepatitis C Virus - Findings advance knowledge in hepatitis C virus research

Hepatitis C Virus - HCV NS3-4A Ser protease is inhibited by orally bioavailable compound

Hepatitis C Virus - HCV protease inhibitor suppresses polyprotein maturation and enhances interferon activity

Hepatitis C Virus - Hepatitis C virus replicon-expressed NS5A can be tagged

Hepatitis C Virus - Human ribosomal protein L18a interacts with HCV internal ribosome entry site

Hepatitis C Virus - Potent hepatitis C virus protease inhibitors are derived from macrocycles

Hepatitis C Virus - Researchers detail new studies and findings in the area of hepatitis C virus

Hodgkin-Reed-Sternberg Cells - Hodgkin-Reed-Sternberg cells inhibit apoptosis via caspase-3 interference

Huntington Disease - PolyGlu-induced toxicity is suppressed by ubiquilin in cell and animal models of Huntington disease

Hypertension - In hypertensive conditions, bradykinin B1 receptor may attenuate cardiac remodeling

Hypertension - Researchers provide details of new studies and findings in the area of hypertension

Hypoxia - Amyloid peptides mediate hypoxic increase of L-type Ca2+ channels in central neurones

Hypoxia - Hypoxia-inducible factor is stabilized by labile iron modulation in macrophages

Imaging - Real-time PCR and computerized-image analysis quantitates KSHV viral copies/cell

Immunotherapy - Tolerance by transcutaneous immunization through UV-irradiated skin is dependent on IL-10

Infection Control - Health Protection Agency's partner launches surgical instrument decontamination product

Infectious Diseases -  Coxiella burnetii infection involves CD28

Inflammatory Bowel Disease - Antihuman CD48 antibody treatment may represent a novel therapy for IBD patients

Inflammatory Bowel Disease - Inhibition of CHI3L1 activity may be a novel therapeutic approach for IBD

Influenza Vaccines - Reports add new data to influenza vaccines research

Influenza Vaccines - Researchers describe findings in influenza vaccines studies

Ischemia - Ceramide-induced preconditioning of ischemic-reperfused heart involves reactive oxygen species

Ischemia - Myocardial ischemic injury is modulated by receptor for advanced-glycation end products

Ischemia - Reperfusion injury protected against by selective inhibitor of Na+/Ca2+ exchanger, SEA0400

Ischemia - Studies add new findings to ischemia body of knowledge

Legal Issues - Cardium announces patent wins over Boston Scientific and Arch Development Corporation

Leishmaniasis Vaccine - Immunodominant antigens useful for leishmaniasis detection are identified

Leptospirosis Vaccine - Leptospiral protein protects against Leptospira interrogans

Leukemia - Acute myeloid leukemia patients prognosticated by BAALC expression

Leukemia - Link between leukemia prognosis and multidrug resistance-related proteins studied

Leukemia - Recent findings in leukemia described

Leukemia - STAT5b accelerates differentiation into mature dendritic cells

Listeriosis Vaccine - MHC Ib-specific T cells are nonredundant in Listeria host defense

Liver Cancer - Hepatocellular cancer prognosis after resection predicted by chemokine receptor

Liver Cancer - Hepatocellular carcinoma prodrug cell killing activity clarified

Lung Cancer - Lung cancer analyzed at high-resolution by whole genome tiling path array CGH

Lung Cancer - Lung cancer apoptosis enhanced by adenylate cyclase toxin

Lung Cancer - Lung carcinoma cell growth is suppressed by rosiglitazone via two pathways

Market Analysis - Frost & Sullivan reports European drug discovery market on expansion course

Market Analysis - Report suggests technologies such as RNAi and metabolic are promising in drug target validation

Matrix Metalloproteinases - Matrix metalloproteinase expression can be altered by interleukin

Medical Devices - Microfluidic biochip developed for leukemia genomic analysis

Melanoma - Metastatic melanoma and poor survival associate with heightened YKL-40 levels

Melioidosis Vaccine - DNA vaccine protects against Burkholderia pseudomallei infection

Mental Health - Memantine antidepressant effects mediated via L-arginine-NO-cGMP pathway

Mergers & Acquisitions - IRIS International acquires Leucadia, enters the molecular-diagnostics market

Mergers & Acquisitions - Serologicals agrees to acquire Linco combining immunoassay products, CRO services

Mergers & Acquisitions - Teva increases equity ownership in Tianjin Hualida Biotechnology from 45 to 60%

Mutagenesis - Mouse lymphoma thymidine kinase gene mutation assay is described

Mycobacterium Tuberculosis -  Mycobacterium tuberculosis PE and PPE genes clusters are organized in operons

Myeloma - Apoptosis sensitization in multiple myeloma involves repressed hTERT transcription

Myocardial Infarction - In rats with chronic MI, gap junction modifier rotigaptide reduces infarct size

Myocardial Infarction - Post-myocardial infarction LV remodeling could be prevented with selective MMP inhibition

Nasal Cancer - Nasopharyngeal carcinoma suppressed by 14-3-3 sigma in mice

Natural Products - Oyster extract induces triglyceride-lowering activity and antihypertensive effect rat model

Nephrology - Shiga toxin-2 holotoxin and B subunit toxic to renal tubular epithelial cells

Nephrology - TLR2 mediates early proximal tubule cell inflammation in kidneys

Neural Tube Defects - Valproic acid-induced birth defects prevented by folic acid and pantothenic acid in mice

Neuroscience - Amyloid precursor protein interacts with a neuronal trafficking receptor

Neuroscience - Erythropoietin reduces perihematomal inflammation and cell death

Neuroscience - N-methyl-D-aspartate receptor ethanol sensitivity may be regulated by NR1 domains

Neuroscience - Researchers' findings advance neuroscience research

Neuroscience - Ubiquitin-proteasome pathway is stimulated through Ntan1 expression

Neurotoxin Vaccine - Botulinum neurotoxin heavy chain fragment is purified in Pichia pastoris

Obesity Pathogenesis - Correlation between serum total sialic acid and adenosine deaminase discovered in obese

Obstetrics - Reports advance knowledge in obstetrics research

Oncology - Findings describe new data in oncology research

Oncology - Reports describe recent advances in oncology research

Ophthalmology - Physiological pathways differently regulate collagen gel contraction in the eye

Ophthalmology - Recent findings in ophthalmology provide new insights

Ophthalmology - Retinopathy of prematurity may be a product of tubedown-1 loss

Oral Cancer - Oral cancer may be fueled by fibroblast growth factor-2

Oral Cancer - Oral squamous cell carcinoma microarray analysis elucidates gene expression

Osteosarcoma - Osteosarcoma apoptosis induced by p33(ING1b) tumor suppressor and p53

Ovarian Cancer - Multimarker assay for ovarian cancer most promising to date

Ovarian Cancer - Ovarian cancer prognosticated by antibody immunity to the p53 oncogenic protein

Pancreatic Cancer - Pancreatic cancer cell invasion declines upon Notch-1 inhibition

Pancreatic Cancer - Pancreatic cancer diagnosis via RT-PCR for alpha4GnT shows promise

Pancreatic Cancer - Recent studies add new data to pancreatic cancer research

Paracoccidioidomycosis - gp43-pulsed dendritic cells increase pulmonary paracoccidioidomycosis

Parasitology - Chagas parasite Trypanosoma cruzi glutamate transport characterized

Patents - EGene receives notice it will be granted Chinese patent for DNA analyzer technology

Patents - U.S. patent issued to Isis Pharmaceuticals for antisense drugs with modified sugars

Pediatric Cancer - Neuroblastomas reveal growth, angiogenesis, and apoptosis in new model systems

Pediatric Cardiology - Cardiopulmonary bypass and underlying heart defect influence connexin43 expression

Penicilliosis -  Penicillium marneffei conidia adhesion mediated by novel glycosaminoglycans

Personnel - Duska Therapeutics announces new chief financial officer

Personnel - Immune Response Corp. forms scientific advisory board to guide multiple sclerosis research

Personnel - Matritech adds David Kolasinski as vice president of sales

Pharmaceutical Research - Atorvastatin modulates endothelial cell-derived immunoactive proteins

Pleural Mesothelioma - New human malignant pleural mesothelioma models produce excess VEGF

Pneumococcal Pneumonia - Pneumococcal endonuclease allows escape from neutrophil extracellular traps

Polymerase Chain Reaction - DNA and RNA references for qRT-PCR assays in cervical cells are reported

Prion Disease - Data advance knowledge in prion disease research

Prions - Genencor International launches first enzyme technology for prion decontamination

Product Licensing - Astellas, Immuno-Biological Labs sign license agreement to develop osteopontin antibodies

Progenitor Cells - Progenitor cell differentiation and beta-catenin turnover is controlled by Cdc42

Prognostics - Colon and urothelial cancer survival linked to transketolase TKTL1 expression

Prostate Cancer - New findings in the area of prostate cancer described

Prostate Cancer Vaccines - Researchers provide details of new studies and findings in the area of prostate cancer vaccines

Proteomics - Atopic dermatitis development linked to IL-31 expression

Proteomics - BNIP3 plays a key role in hypoxia-induced death of normal and malignant cells

Proteomics - Cell viability requires Repo-Man recruitment of protein phosphatase to chromatin

Proteomics - Conway Institute licenses new technology for new approach to 2D proteomics research

Proteomics - Data advance knowledge in proteomics research

Proteomics - Elevated homocysteine reduces ApoA-I expression in hyper-homocysteinemic mice

Proteomics - MDSC's feasibility for characterizing therapeutic protein solutions needs more assessment

Proteomics - Stromal protein modulates tumor growth and invasion in a site-specific fashion

Proteomics - Syntaxin-3, OSBP-related protein 3, PPAR-gamma and glycophorin linked to adipogenesis

Proteomics - Thermo Electron expands kits for identification and absolute quantification of peptides

Pulmonary Hypertension - Idiopathic pulmonary arterial hypertension linked to high plasma MCP-1

Pulmonary Medicine - Researchers' work adds to pulmonary medicine body of knowledge

Respiratory Syncytial Virus - RSV G protein fragment and CTL epitope fusion protein induces balanced immunity

Retinitis Pigmentosa - Retinal rds-peripherin is suppressed by RNAi and can be replaced

Rotavirus Vaccine - Rectally delivered vaccine protects mice against rotavirus infection

SARS - Recent findings in SARS described

SARS Vaccine - SARS vaccine candidates were evaluated in mice challenged with SARS coronavirus

Skin Cancer - Melanoma risk may be lowered with 3,4-DHAP treatment

Squamous Cell Carcinoma - Prognosis of quid chewing-related oral squamous cell carcinomas linked to c-Jun activation

Squamous Cell Carcinoma - Prognosis of squamous cell carcinoma of the lung linked to DNA ploidy

Stem Cell Research - Fibulin-2 is important for smooth muscle cell migration

Stem Cell Research - Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

Thalassemia - Beta-thalassemia intermedia displays genotypic heterogeneity

Tissue Engineering - Demineralized bone matrix gelatin scaffold developed for osteochondral tissue engineering

Toxoplasma Gondii -  Toxoplasma gondii-regulated transcriptional responses screened in LPS-activated macrophages

Trachomatous Conjunctivitis - Trachoma progression is a derivative of fibrotic and angiogenic activity

Transplant Medicine - Recent studies add new data to transplant medicine research

Trypanosoma Cruzi -  Trypanosoma cruzi infection is blocked by laminin gene silencing

Trypanosomiasis Vaccine - DNA vaccine controls Trypanosoma cruzi infection

Tularemia Vaccine -  Francisella tularensis grey variants do not induce immunity

Upper Respiratory Tract Infections -  Moraxella catarrhalis serum resistance mediated by UspA2 vitronectin binding

Vaccine Vector - MHC-haplotype influences primary immune responses to immunodominant peptide

Virology - New findings in the area of virology detailed

Virology - Research in virology provides new insights

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