Angiology

In stable angina, inflammation marker hs-CRP and complement activation marker C3a are elevated

Published in Proteomics Weekly, April 24th, 2006

Both high sensitivity C-reactive protein (hs-CRP), a marker of inflammation and C3a, a marker of complement activation are elevated in patients with unstable angina pectoris.

According to recent research from Australia, "Endothelial dysfunction plays an important role in the pathogenesis of coronary artery disease (CAD). Apart from traditional risk factors, complement activation and inflammation may trigger and sustain endothelial dysfunction."

University of Queensland researchers K.M. Kostner and colleagues explained, "We sought to assess the association between endothelial function, high sensitivity C-reactive protein (hs-CRP) and markers of...

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Source: Proteomics Weekly (2006-04-24)

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