Anthrax Vaccine

Persistence of immunity following anthrax vaccination was examined

Published in Proteomics Weekly, April 24th, 2006

Scientists examine the persistence of immunity following anthrax vaccination in a recent issue of Clinical and Vaccine Immunology.

"Anthrax toxin consists of protective antigen (PA) and two toxic components, lethal factor (LF) and edema factor (EF). PA binds to mammalian cellular receptors and delivers the toxic components to the cytoplasm. PA is the primary antigenic component of the current anthrax vaccine. Immunity is due to the generation of antibodies that prevent the PA-mediated internalization of LF and EF. In this study, we characterized sera obtained from vaccinated military personnel," investigators in the United States report.

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Source: Proteomics Weekly (2006-04-24)

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