Mycobacteria
Findings from the United States and France describe new data in mycobacteria research
Published in Proteomics Weekly, May 15th, 2006
Study 1: Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.
According to recent research from the United States, "Mycobacterium tuberculosis has evolved to persist in host macrophages, where it faces a nutrient-poor environment and is exposed to oxidative and nitrosative stress.
"To defend itself against oxidative/nitrosative stress, M. tuberculosis expresses an NADH-dependent peroxidase and peroxynitrite reductase that is encoded by ahpC, ahpD, lpd, and dlaT."
"In...
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Source: Proteomics Weekly (2006-05-15)
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