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Bladder Cancer

Bladder cancer prognosis linked to enhanced expression of peroxiredoxin I and VI

Published in Proteomics Weekly, May 15th, 2006

Bladder cancer prognosis could be linked to enhanced expression of peroxiredoxin (PRDX) I and VI.

"PRDXs are antioxidant enzymes that have an important role in cell differentiation, proliferation and apoptosis. We investigated whether PRDX I and VI expression is related to bladder cancer. PRDX I and VI mRNA levels were examined in 149 tumor specimens in patients with primary bladder cancer, in 19 specimens with corresponding normal-appearing bladder mucosa surrounding cancer and in 18 with normal bladder mucosa using real-time polymerase chain reaction," scientists in South Korea reported.

"PRDX I and VI expression in bladder cancer (.6644 and .1455...

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