Allergy & Immunology
Allergen-induced peribronchial angiogenesis is inhibited by immunostimulatory DNA
Published in Proteomics Weekly, May 15th, 2006
"Airway remodeling in asthma is associated with angiogenesis. We have examined whether immunostimulatory sequences of DNA (ISSs) inhibit allergen-induced airway angiogenesis and expression of angiogenic cytokines in a mouse model of airway remodeling," wrote S.Y. Lee and colleagues, University of California, San Diego.
They explained, "Mice sensitized to ovalbumin were challenged repetitively with ovalbumin for three months to develop airway remodeling and angiogenesis. Levels of angiogenesis were...
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Source: Proteomics Weekly (2006-05-15)
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