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Diabetes

New findings from Japan and the United States in the area of diabetes described

Published in Proteomics Weekly, May 22nd, 2006

Investigators in Japan and the United States have published new diabetes data.

Study 1: Angiotensin-converting enzyme (ACE) correlates with angiogenesis factors in diabetic retinopathy.

Scientists in Japan conducted a study "to investigate the involvement of ACE with angiogenic factors, vascular endothelial growth factor (VEGF), and matrix metalloproteinase (MMP)-9 in the vitreous of eyes with proliferative diabetic retinopathy (PDR)."

"ACE activity in the vitreous was measured by using a synthetic substrate for ACE. VEGF and MMP-9 concentrations were determined by enzyme-linked immunosorbent assay. Vitreous ACE activity was...

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