Angiology

Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells

Published in Proteomics Weekly, May 22nd, 2006

Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.

According to a report from the United States, "Xanthine oxidoreductase (XOR) activity has been previously noted to be responsive to changes in O₂ tension. While prior studies have focused on the extremes (0-3% and 95-100%) of O₂ tensions, we report the influence of 10% O₂ on endothelial cell XOR, a concentration resembling modest arterial hypoxia commonly found in patients with chronic cardiopulmonary diseases."

E.E. Kelley and colleagues at University of Alabama in Birmingham wrote, "Exposure of bovine aortic endothelial cells...

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Source: Proteomics Weekly (2006-05-22)

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