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Squamous Cell Carcinoma

Investigators at Fourth Military Medical University, Department of Oral Biology target squamous cell carcinoma

Published in Proteomics Weekly, January 1st, 2007

New investigation results, "Expression of urokinase-type plasminogen activator receptor is correlated with metastases of lingual squamous cell carcinoma," are detailed in a study published in British Journal of Oral & Maxillofacial Surgery. "Lingual squamous cell carcinoma is common and the survival rate is relatively low. The invasion of cancer cells from the primary tumor into the surrounding tissue is an early step in the process of metastasis and urokinase-type plasminogen activator receptor (uPAR) is a vital mediator of cellular migration in some carcinomas," researchers in People's Republic of China report.

"By binding urokinase-type plasminogen activator, uPAR...

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