Hepatitis C Virus Vaccines
Study results from Second Military Medical University, Department of Microbiology provide new insights into hepatitis c virus vaccines
Published in Proteomics Weekly, January 1st, 2007
Fresh data on hepatitis C virus are presented in the report "Construction and characterization of an HCV-derived multi-epitope peptide antigen containing B-cell HVR1 mimotopes and T-cell conserved epitopes. Hepatitis C (HCV) genome is highly variable, particularly in the hypervariable region 1 (HVR1) of its E2 envelope gene. The variability of HCV genome has been a major obstacle for developing HCV vaccines," scientists in Shanghai, People's Republic of China report.
"Due to B-cell HVR1 mimotopes mimicking the antigenicity of natural HVR1 epitopes and some T-cell epitopes from the consensus sequence of HCV genes conserving among the different HCV genotypes, we...
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Source: Proteomics Weekly (2007-01-01)
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