Cancer Gene Therapy
Research in the area of cancer gene therapy reported from Uppsala University, Department of Surgical Sciences
Published in Proteomics Weekly, February 19th, 2007
A report, "Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours," is newly published data in Clinical Endocrinology. "We and others have reported loss of heterozygosity (LOH) on chromosome 3p25 in sporadic malignant pancreatic endocrine tumours (PETs). A common region of deletion on chromosome 3p25 contains numerous genes, including VHL and PPARgamma, that have been excluded previously as candidate tumor suppressor genes by DNA sequencing analysis," researchers in Uppsala, Sweden report.
"We have analysed whether WNT7A or HDAC11 was biallelically inactivated in a group of well-characterized PETs....
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Source: Proteomics Weekly (2007-02-19)
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