Cervical Cancer
Findings from Korea Advanced Institute of Science and Technology advance knowledge in cervical cancer
Published in Proteomics Weekly, February 19th, 2007
Current study results from the report, "Human papillomavirus type 16 E6 protein interacts with cystic fibrosis transmembrane regulator-associated ligand and promotes E6-associated protein-mediated ubiquitination and proteasomal degradation," have been published. According to recent research from Korea, "The PDZ proteins such as hDLG, hScrib and MAGIs function as the membrane-associated protein scaffolds and have been shown to interact with the high-risk human papillomavirus (HPV) E6s. In this report, we identify a Golgi-associated PDZ protein, cystic fibrosis transmembrane regulator-associated ligand (CAL) as a cellular target of HPV16 E6 by the proteomic approach."
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Source: Proteomics Weekly (2007-02-19)
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