Cancer
Reports on cancer findings from Loma Linda University provide new insights
Published in Proteomics Weekly, February 26th, 2007
Data detailed in "Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1" have been presented. According to a study from the United States, "Alterations in cytosine methylation patterns are usually observed in human tumors. The consequences of altered cytosine methylation patterns include both inappropriate activation of transforming genes and silencing of tumor suppressor genes."
"Despite the biological effect of methylation changes, little is known about how such changes are caused. The heritability of cytosine methylation patterns from parent to progeny cells is attributed to the fidelity of the...
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Source: Proteomics Weekly (2007-02-26)
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