Leukemia

Findings from University of Munster provide new insights into leukemia

Published in Proteomics Weekly, February 26th, 2007

Current study results from the report, "DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia," have been published. According to a study from Munster, Germany, "Epigenetic changes play an important role in leukemia pathogenesis. DNA methylation is among the most common alterations in leukemia."

"The potential role of DNA methylation as a biomarker in leukemia is unknown. In addition, the lack of molecular markers precludes minimal residual disease (MRD) estimation for most patients with hematologic malignancies. We analyzed the potential of aberrant DNA promoter methylation as a biomarker for MRD in acute...

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Source: Proteomics Weekly (2007-02-26)

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