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HIV/AIDS

Results with New Integrase Inhibitor Plus FUZEON and Boosted Protease Inhibitor Show Remarkable Undetectable Rate of 98 Percent in Treatment-Experienced HIV Patients

Published in Proteomics Weekly, March 12th, 2007

Virtually all patients (98 percent) who received the investigational integrase inhibitor raltegravir, along with FUZEON(R) (enfuvirtide) and an active boosted protease inhibitor (darunavir), achieved undetectable levels of HIV (less than 400 copies/mL of blood), according to new interim 16-week clinical data presented this week at the 14th annual Conference on Retroviruses and Opportunistic Infections (CROI) in Los Angeles. Such a high response rate has never been seen in patients who have developed resistance to at least one agent in each of the first three classes of antiretrovirals.

FUZEON, co-developed by Roche and Trimeris (Nasdaq: TRMS), is the first and only...

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