Biomedical Engineering
Data on biomedical engineering detailed by researchers at Yamagata University, Department of Orthopaedic Surgery
Published in Proteomics Weekly, March 12th, 2007
Data detailed in "Upregulation of matrix metalloproteinase (MMP)-1 and its activator MMP-3 of human osteoblast by uniaxial cyclic stimulation" have been presented. According to recent research from Yamagata, Japan, "Proper mechanical loading is essential for bone remodeling and maintenance of human skeletal system. Matrix metalloproteinases (MMPs) are secreted by mesenchymal stromal lining cells and osteoblasts to prepare the initiation sites for osteoclastic bone resorption at the beginning of the remodeling cycle."
"However, only a few studies have addressed the effect of mechanical stress on MMPs and their endogenous tissue inhibitors of matrix metalloproteinases...
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Source: Proteomics Weekly (2007-03-12)
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