Proteomics
Study findings from University of Wroclaw broaden understanding of proteomics
Published in Proteomics Weekly, April 16th, 2007
Research findings, "Bivalent peptides as models for multimeric targets of PDZ domains," are discussed in a new report. "PDZ domains are among the most common modules in eukaryotic, including human, genomes. They are found exclusively in large, multidomain cytosolic proteins--often with other domains that belong to a variety of families--and are involved in a plethora of physiological and pathophysiological events," scientists writing in the journal ChemBioChem report.
"PDZ domains mediate protein-protein interactions by binding to solvent-exposed and extended C-terminal short fragments of membrane-associated proteins, such as receptors and ion channels. Most of...
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Source: Proteomics Weekly (2007-04-16)
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