Cell Biology
Research from Ewha Womans University, Center for Cell Signaling broadens understanding of cell biology
Published in Proteomics Weekly, April 16th, 2007
Data detailed in "Two axes in platelet-derived growth factor signaling: tyrosine phosphorylation and reactive oxygen species" have been presented. "The tyrosine phosphorylation cascade is a hallmark of platelet-derived growth factor (PDGF)-induced signal transduction. The amplitude and propagation of the tyrosine phosphorylation signal relies on the balance between tyrosine kinase and tyrosine phosphatase," scientists in Seoul, Korea report.
"The tyrosine kinase is latent in the absence of stimulation, whereas the tyrosine phosphatase is highly and constitutively active. Therefore, the kinase activation should be accompanied by temporal and spatial inactivation of...
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Source: Proteomics Weekly (2007-04-16)
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