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Cell Biology

Study data from University of Freiburg, Max Planck Institute for Immunobiology provide new insights into cell biology

Published in Proteomics Weekly, April 16th, 2007

Scientists discuss in "Association of protein kinase C-delta with the B cell antigen receptor complex" new findings in cell biology. According to recent research from Freiburg, Germany, "Protein kinase C (PKC)-delta is a diacylglycerol-dependent, calcium-independent novel PKC isoform and has been demonstrated to exert negative regulatory functions in B lymphocytes as well as in mast cells. Whereas in mast cells PKC-delta functionally interacts with the high-affinity receptor for IgE, FcepsilonR1, no such association has been described for the B cell antigen receptor (BCR)."

"In this report, for the first time, we demonstrate the interaction of PKC-delta with different...

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