Colon Cancer

Study results from University of Tokyo, Department of Gastroenterology provide new insights into colon cancer

Published in Proteomics Weekly, April 23rd, 2007

Fresh data on colon cancer are presented in the report "Absence of tyrosine kinase mutations in Japanese colorectal cancer patients. Tyrosine kinases, which are important regulators of intracellular signal-transduction pathways, have mutated forms that are often associated with oncogenesis and are attractive targets for therapeutic intervention. Recently, systematic mutational analyses of tyrosine kinases revealed that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases," scientists writing in the journal Oncogene report.

"To further explore these mutations, we examined all reported mutations of NTRK3, FES, KDR, EPHA3,...

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Source: Proteomics Weekly (2007-04-23)

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