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HIV/AIDS Therapy

Research on HIV/AIDS therapy reported by scientists at University of Sao Paulo

Published in Proteomics Weekly, July 9th, 2007

Investigators publish new data in the report "Structural characterization of B and non-B subtypes of HIV-protease: insights into the natural susceptibility to drug resistance development." According to recent research from Sao Carlos, Brazil, "Although a majority of HIV-1 infections in Brazil are caused by the subtype B virus (also prevalent in the United States and Western Europe), viral subtypes F and C are also found very frequently. Genomic differences between the subtypes give rise to sequence variations in the encoded proteins, including the HIV-1 protease."

"The current anti-HIV drugs have been developed primarily against subtype B and the effects arising from...

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