Breast Cancer Genetics

Study data from Vanderbilt University, Center for Human Genetics Research update knowledge of breast cancer genetics

Published in Proteomics Weekly, September 3rd, 2007

New investigation results, "Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer," are detailed in a study published in Cancer Epidemiology, Biomarkers & Prevention. "The availability of large amounts of genomic DNA (gDNA) is the limiting factor for many of the molecular biology assays in genetic epidemiologic studies. Whole-genome amplification using multiple displacement amplification is used to amplify a representative sample of gDNA from small amounts of gDNA to optimize gDNA yield," scientists in the United States report.

"We collected oral rinse DNA samples through the mail from 3,377 women...

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Source: Proteomics Weekly (2007-09-03)

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