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Dermatology

New dermatology research from J. Listopad and colleagues discussed

Published in Proteomics Weekly, September 3rd, 2007

New investigation results, "Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells," are detailed in a study published in Experimental Dermatology. "Heme oxygenase-1 (HO-1) is increased in psoriatic skin. We asked for the impact of physiological and pharmacological HO-1 induction on skin immunity and the mechanisms involved in HO-1-induced immunomodulation," scientists in Berlin, Germany report.

"We found cutaneous HO-1 expression upregulated comparable with suppressors of cytokine signalling (SOCS)1 and SOCS3 in psoriasis and atopic eczema and temporarily increased in murine ovalbumin-induced...

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