Delirium

'Alzheimer's Gene' Linked to Increased Risk of Postoperative Delirium

Published in Proteomics Weekly, September 3rd, 2007

Elderly patients who carry a gene associated with an increased risk of Alzheimer's disease and dementia have higher rates of postoperative delirium after major surgery.

The September issue of the journal Anesthesiology features a study linking the apolipoprotein E (APOE) e4 gene variant to the risk of postoperative delirium, a common postoperative complication in elderly patients. "Our study showed that APOE e4 carrier status was associated with an increased risk for early postoperative delirium, after controlling for known demographic and clinical risk factors," says Dr. Jacqueline M. Leung of University of California, San Francisco.

The study...

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Source: Proteomics Weekly (2007-09-03)

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