Hepatitis C Virus
Research on hepatitis C virus reported by scientists at Abbott Laboratories
Published in Proteomics Weekly, September 24th, 2007
Research findings, "Longer wavelength fluorescence resonance energy transfer depsipeptide substrates for hepatitis C virus NS3 protease," are discussed in a new report. According to recent research from the United States, "Maturation of the hepatitis C virus (HCV) polyprotein occurs by a series of proteolytic processes catalyzed by host cell proteases and the virally encoded proteases NS2 and NS3. Although several peptidomimetic inhibitors of NS3 protease have been published, only a few small molecule inhibitors have been reported."
"In an effort to improve screening efficiency by minimizing the spectral interference of various test compounds, a substrate that contains...
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Source: Proteomics Weekly (2007-09-24)
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