Gene Therapy

New mechanism discovered for DNA recombination and repair

Published in Proteomics Weekly, September 24th, 2007

A biochemistry research team led by Dr. Andrew H.-J. Wang and Dr. Ting-Fang Wang at the Institute of Biological Chemistry, Academia Sinica(IBCAS), has discovered that the RecA family recombinases function as a new type of rotary motor proteins to repair DNA damages.

The team has recently published two structural biology articles related to RecA family recombinases. One paper is to be published in the online, open-access journal PLoS ONE on September 12, 2007 and the other has been already published in the Nucleic Acids Research on Feb. 28, 2007.

Homologous recombination (HR) is a mechanism that repairs damaged DNA with perfect accuracy, it utilizes...

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Source: Proteomics Weekly (2007-09-24)

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