Neuroblastoma Genetics
Researchers from National Institute for Cancer Research detail findings in neuroblastoma genetics
Published in Proteomics Weekly, October 1st, 2007
A new study, "Identification and characterization of DNA imbalances in neuroblastoma by high-resolution oligonucleotide array comparative genomic hybridization," is now available. According to a study from Genoa, Italy, "Neuroblastoma (NB) is a pediatric tumor characterized by high genetic heterogeneity. Although the prognostic significance of some genomic abnormalities (i.e., MYCN amplification, 1p loss, and 17q gain) is recognized, genes that are involved in chromosome rearrangements remain largely unknown."
"Considerable progress has been made over the last years in characterizing DNA abnormalities by metaphase comparative genomic hybridization (mCGH) and array CGH...
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Source: Proteomics Weekly (2007-10-01)
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