Suicide
Scientists at University of Cantabria release new data on suicide
Published in Proteomics Weekly, October 1st, 2007
Data detailed in "Analysis of DNA processing reactions in bacterial conjugation by using suicide oligonucleotides" have been presented. According to recent research from Santander, Spain, "Protein TrwC is the conjugative relaxase responsible for DNA processing in plasmid R388 bacterial conjugation. TrwC has two catalytic tyrosines, Y18 and Y26, both able to carry out cleavage reactions using unmodified oligonucleotide substrates."
"Suicide substrates containing a 3'-S-phosphorothiolate linkage at the cleavage site displaced TrwC reaction towards covalent adducts and thereby enabled intermediate steps in relaxase reactions to be investigated. Two distinct covalent...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Proteomics Weekly
Source: Proteomics Weekly (2007-10-01)
More Articles from Proteomics Weekly
- Apoptosis
New cell death pathway involved in sperm development - Brain Cancer
Study suggests brain tumors need treatment with multiple 'targeted' drugs - Cancer Gene Therapy
T vs. B: Re-engineered Human T Cells Effectively Target and Kill Cancerous B Cells - Cancer Vaccines
M.D. Anderson-led team reports possible key to autoimmune disease - Enzyme Research
Scientists learn structure of enzyme in unusual virus - Enzyme Research
What makes a fungus virulent? It's lipase - More from this issue of Proteomics Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
