Published in Proteomics Weekly, January 14th, 2008
"Here, we examine the mechanisms of the antiapoptotic role of NADPH oxidase. We hypothesized that ROSS produced by NADPH oxidase inhibit key protein tyrosine phosphatases (PTPs) and thus sustain the activation of kinases mediating antiapoptotic pathways in PaCa cells. Transfections and pharmacologic inhibition were used...
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