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Colon Cancer Therapy

Reports from Wayne State University, Karmanos Cancer Institute add new data to research in colon cancer therapy

Published in Proteomics Weekly, January 14th, 2008

Data detailed in 'Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer' have been presented. According to recent research from the United States, "The cyclooxygenase-2 (COX-2) enzyme plays a major role in tumor progression and resistance to chemotherapy. A Phase-II study was undertaken to determine the activity of a dose attenuated schedule of irinotecan, capecitabine, and the COX-2 inhibitor celecoxib in patients with advanced colorectal cancer."

"The eligibility criteria included a pathologically or cytologically confirmed diagnosis of adenocarcinoma of the colon or rectum that was metastatic. Patients...

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