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Mass Spectrometry

Research from Tata Institute of Fundamental Research has provided new information about mass spectrometry

Published in Proteomics Weekly, February 4th, 2008

Fresh data on mass spectrometry are presented in the report 'Exploring the cooperativity of the fast folding reaction of a small protein using pulsed thiol labeling and mass spectrometry.' "It has been difficult to obtain directly residue-specific information on side chain packing during a fast (ms) protein folding reaction. Such information is necessary to determine the extent to which structural changes in different parts of the protein molecule are coupled together in defining the cooperativity of the overall folding transition," investigators in Bangalore, India report.

"In this study, structural changes occurring during the major fast folding reaction of the small...

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