Enzyme Research
Research from Tokyo Metropolitan Institute of Public Health in enzyme research provides new insights
Published in Proteomics Weekly, March 17th, 2008
Researchers detail in 'In vitro screening assay for detecting aromatase activity using rat ovarian microsomes and estrone ELISA,' new data in enzyme research. According to recent research from Tokyo, Japan, "Aromatase, a key steroidogenic enzyme that catalyses the conversion of androgens to estrogens, present a target for endocrine disrupting chemicals. However, little is known about the effect of pollutants on aromatase enzymes."
"In this study, we first optimized a non-radioisotope aromatase assay using rat ovarian microsomes in vitro and measuring the estrone level with an enzyme-linked immunosorbent assay (EIA method). The sensitivity of the EIA method was about ten...
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Source: Proteomics Weekly (2008-03-17)
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