Life Sciences
Researchers from Kitasato University, Department of Anatomy describe findings in life sciences
Published in Proteomics Weekly, March 17th, 2008
New investigation results, 'IQ-ArfGEF/BRAG1 is a guanine nucleotide exchange factor for Arf6 that interacts with PSD-95 at postsynaptic density of excitatory synapses,' are detailed in a study published in Neuroscience Research. "ADP ribosylation factor 6 (Arf6) is a small GTPase that regulates dendritic differentiation possibly through the organization of actin cytoskeleton and membrane traffic. Here, we characterized IQ-ArfGEF/BRAG1, a guanine nucleotide exchange factor (GEF) for Arf6, in the mouse brain," scientists writing in the journal Neuroscience Research report.
"In vivo Arf pull down assay demonstrated that IQ-ArfGEF/BRAG1 activated Arf6 more...
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Source: Proteomics Weekly (2008-03-17)
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