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Tissue Engineering

New tissue engineering study findings have been reported by researchers at University of Oregon, Institute of Molecular Biology

Published in Proteomics Weekly, March 17th, 2008

Data detailed in 'Direct spectroscopic study of reconstituted transcription complexes reveals that intrinsic termination is driven primarily by thermodynamic destabilization of the nucleic acid framework' have been presented. "Changes in near UV circular dichroism (CD) and fluorescence spectra of site-specifically placed pairs of 2-aminopurine residues have been used to probe the roles of the RNA hairpin and the RNA-DNA hybrid in controlling intrinsic termination of transcription. Functional transcription complexes were assembled directly by mixing preformed nucleic acid scaffolds of defined sequence with T7 RNA polymerase (RNAP)," scientists writing in the Journal of Biological...

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