Arthritis

Recent studies by G. Orozco and co-authors add new data to arthritis findings

Published in Proteomics Weekly, March 17th, 2008

In this recently published article, scientists in Granada, Spain conducted a study "To analyse the relationship between the presence of auto-antibodies [rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP)], HLA-DRB1 alleles and PTPN22 1858 C/T polymorphism and test the value of their combination as susceptibility markers for rheumatoid arthritis (RA). Patients with early arthritis were included."

"At entry in the cohort or during follow-up, 191 patients fulfilled the criteria for RA and 184 individuals suffered from other arthropathies. RF was measured by nephelometry and anti-CCP antibody by enzyme-linked immunosorbent assay. HLA class II alleles...

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Source: Proteomics Weekly (2008-03-17)

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